about
P688
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cellsA comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicityPluripotency factors regulate definitive endoderm specification through eomesoderminTsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogrammingCore transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determinationSox2 and Pou2f1 interact to control lens and olfactory placode developmentThe structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platformsAn Oct4-centered protein interaction network in embryonic stem cellsDevelopmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewalDifferential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cellsRole of Sox2 in the development of the mouse neocortexExpression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesisEYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner earThe amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivativesFbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse developmentDissecting self-renewal in stem cells with RNA interferenceNotch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathwayInvolvement of SOX proteins in lens-specific activation of crystallin genesSox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brainPwp1 is required for the differentiation potential of mouse embryonic stem cells through regulating Stat3 signalingES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250aSOX7 and GATA-4 are competitive activators of Fgf-3 transcriptionKlf4 interacts directly with Oct4 and Sox2 to promote reprogrammingMultiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endodermA positive regulatory role for the mSin3A-HDAC complex in pluripotency through Nanog and Sox2Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cellsInhibition of DNA binding of Sox2 by the SUMO conjugationMultipotent cell lineages in early mouse development depend on SOX2 functionA dominant-negative form of mouse SOX2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cellsCooperative functions of Hes/Hey genes in auditory hair cell and supporting cell developmentSox1 directly regulates the gamma-crystallin genes and is essential for lens development in miceSox2 is required for development of taste bud sensory cellsSox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiationSox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewalCdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectodermNew POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2Sox2 is required for sensory organ development in the mammalian inner earSox9 plays multiple roles in the lung epithelium during branching morphogenesis
P921
Q24294207-3DD0BB1F-A78C-4BFF-997E-5D9685676E61Q24309204-CFD9F645-BE9E-4C77-9E77-D8F18C29839BQ24317850-2E5FFAA9-6098-44CE-B248-EE94387B2F32Q24337560-912F8D41-A3DA-4651-9FF1-BFADC1C4A323Q24595783-66ED7FB9-E0EF-46E3-8D22-09ACFD66EE76Q24624936-758522FF-EAE6-4850-A7EF-64AC44AE414BQ24633891-2D13BDF2-CED2-4015-A467-4A11622355E9Q27654478-042DBFB5-6550-4104-9388-3AA00D815D58Q28278599-21383F08-2A56-412F-9282-AA46436A6F9CQ28291574-013BCC00-7EED-4E02-908A-C03D46695EDDQ28504929-3F84C343-AC1B-4BA0-A41C-C6BD240104CAQ28505222-EC0F57A4-3714-4786-B07B-012D20BD45B8Q28505312-963EB3D0-A6B3-40B9-9725-8B9139AE69A7Q28505313-EDABAFAC-2EC2-41B1-8F0D-7FBE7BCC08CAQ28505753-99A80075-7836-4FCE-ACB3-D6AEE65B5861Q28506060-B3E4D9BD-8D5A-449E-9FEC-2CEB84C0E646Q28506535-862D228E-E7A5-4BA9-B03A-58105AF6B7CCQ28506922-311D62A2-AD7E-4834-9EA0-5E663E7BE6E9Q28507459-38F896CC-4E74-46AF-914F-820F86A17569Q28507557-885762D9-9049-4272-8D72-A9629F8D7B49Q28507690-8C31B366-3E68-49E1-A949-02CFECFA6D09Q28507710-D2BC3DEC-F6A5-4050-83F3-82FB55BFD858Q28508327-770474AA-416B-4F5C-9CC1-A3C3AFD8B962Q28508654-E8FE998D-9E53-47A9-B5E4-77A04A1E6A8CQ28508737-0BD1ED04-3E8A-480B-8678-FB6C4728056CQ28510560-DA6EB373-6D4D-4651-9C8B-0A7E23699166Q28510697-78BAFADF-A622-4EB9-BE82-B94503FF35C1Q28511646-47A981FD-EF0E-499E-872E-39067CFDFD15Q28512713-D3A8355D-3E3C-4E51-A94A-33026CD7954CQ28513175-A74B19FE-5C78-494E-9BDF-CD24F5676CCAQ28513634-99C4A106-DF58-4273-9358-4B82C7B8CA48Q28513897-7F592A12-D3E5-4A5F-ACFA-FFEC40A8900EQ28584751-00253264-7CAF-4812-BF0A-2CAF438909A2Q28584894-FB03992C-79D3-4140-A08B-0119D0DB1968Q28585078-95AEA9DC-CF67-4989-9B2D-4801585429C6Q28585188-DFEB8BB7-ED5E-49F8-8315-FEA7C50C5802Q28585309-C7AE8C0C-14A9-4ECD-99BB-CC1F5F16DBE5Q28585451-C42A1CF3-B2F7-4DCA-949D-5A8B70846B27Q28585583-96724BF4-7BD2-4295-9AAC-5EDBDC1078A0Q28585673-E4A19906-5BC0-4ABE-875A-40E917C3FAF8
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in SRY (sex determining region Y)-box 2
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
SRY (sex determining region Y)-box 2
@en
type
label
SRY (sex determining region Y)-box 2
@en
altLabel
SRY-box containing gene 2
@en
Sox2
@en
transcription factor SOX-2
@en
prefLabel
SRY (sex determining region Y)-box 2
@en