about
P688
PITX2 gain-of-function induced defects in mouse forelimb developmentPitx2 is an upstream activator of extraocular myogenesis and survivalPITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications for the pathology of Rieger syndromeIdentification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during developmentPitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetryMolecular pathway for the localized formation of the sinoatrial nodeRegulation of left-right asymmetry by thresholds of Pitx2c activityPitx2 is functionally important in the early stages of vascular smooth muscle cell differentiationModulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesisFormation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signalingPitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushionsCre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleusDistinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fatesFunction of Rieger syndrome gene in left-right asymmetry and craniofacial developmentTbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart fieldDosage requirement of Pitx2 for development of multiple organsThe Pitx2 protein in mouse developmentCited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathwayPitx2 is a critical early regulatory gene in normal cecal developmentIntegration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerismPitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardiumExtraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene doseMyocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programsPitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardiumTbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.
P921
Q24319784-472F1955-2920-417C-AB3C-2FC643315EF0Q24601336-A2D3854D-5AEC-4817-AB2E-58DD7FF5548FQ24670482-F2496D45-60AD-4D37-A9F0-585E822DCA67Q28216579-03AC7203-1063-4E1F-8D65-48215B23CCF6Q28279914-34035742-FC5E-405C-A563-A7DF398DC402Q28284039-0BD6D8F8-B6DB-4C77-90A0-07E65A21EA16Q28505189-5B119572-A4F6-4B21-B2DE-B07A1069B1F5Q28505500-0241BFCC-DAA9-41B6-AF60-85B0DF25908DQ28507487-E51995D1-8FC1-457E-B3C5-2569C032DB06Q28507650-F50D2670-7E18-49BC-9E80-235B0B3259BCQ28509325-4A5FF37F-8140-4120-A4FA-24C5A83CB178Q28509759-E9E49255-8328-4A27-8259-A495F12F9D92Q28510738-CD0902E3-45B4-42D7-AABE-228DC77625CCQ28511131-B5ACA6C1-2523-4331-940F-26AEAE2D74D8Q28511353-A0120F18-3AEA-4997-AD92-28872DEBF229Q28512364-52F577E2-23E8-47D3-83F6-5756FA97D451Q28512581-9D239E6A-ED1E-4316-BE77-C1D967A3F390Q28512878-E0FF6C79-BB5E-433C-8226-0985DB548DE1Q28512908-358056A7-A049-49C0-B840-973488894C4DQ28585538-EABB37C6-C38F-4668-89B8-05C511F2F9B7Q28586161-DD98BB9D-5FFA-4861-B562-97BFE012D51FQ28586386-4605407B-75BB-4012-87FA-7CC44F50E748Q28586689-1E2ACB04-CE3C-4D1B-BB8F-74E46EDE548EQ28586899-70F8FD70-9279-4490-B6C2-6F391FFD80DBQ28588668-B0624654-52C5-4968-9783-C6EBBC403A8BQ28589895-AABC3B0C-CABC-47F2-9D11-348B209E16C8Q28593327-E1730652-2235-4D1A-9B5D-F4D5A120FC1EQ37207678-F8A66861-8E44-4C65-9844-8A660D7DCCF2
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Paired-like homeodomain transcription factor 2
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Paired-like homeodomain transcription factor 2
@en
Paired-like homeodomain transcription factor 2
@nl
type
label
Paired-like homeodomain transcription factor 2
@en
Paired-like homeodomain transcription factor 2
@nl
altLabel
ALL1-responsive protein ARP1
@en
BRX1 homeoprotein
@en
Homeobox protein PITX2
@en
Pitx2
@en
orthodenticle-like homeobox 2
@en
paired-like homeodomain transcription factor Munc 30
@en
pituitary homeobox 2
@en
solurshin
@en
prefLabel
Paired-like homeodomain transcription factor 2
@en
Paired-like homeodomain transcription factor 2
@nl
P527
P637
P680
P681
P682
P705
P352
P637
P279
P31
P352
P637
NP_001035967
NP_001035969
NP_001273871
NP_001273977
XP_006501194
XP_006501195
XP_006501196
XP_030108320
P680
P682
P702
P703
P705
ENSMUSP00000029657
ENSMUSP00000047359
ENSMUSP00000101990
ENSMUSP00000133756
ENSMUSP00000134301
ENSMUSP00000134692
ENSMUSP00000139328