A giant protease with potential to substitute for some functions of the proteasome
about
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosolCells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survivalThe selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic dosesPNG1, a yeast gene encoding a highly conserved peptide:N-glycanaseEpoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activityAlternative Antigen Processing for MHC Class I: Multiple Roads Lead to RomeMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsHybrid molecular structure of the giant protease tripeptidyl peptidase IIRequirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-EMultimeric structure of the secreted meprin A metalloproteinase and characterization of the functional protomerThe transporter associated with antigen processing: function and implications in human diseasesThe ubiquitin-proteasome pathway and proteasome inhibitorsProteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cellsChronic ethanol feeding affects proteasome-interacting proteinsThe ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosisMolecular architecture and assembly mechanism of Drosophila tripeptidyl peptidase II.Purification of the Arabidopsis 26 S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms.EpiJen: a server for multistep T cell epitope prediction.Puromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradationEarly-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency.Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosisIn situ structural studies of tripeptidyl peptidase II (TPPII) reveal spatial association with proteasomesA novel intracellular peptide derived from g1/s cyclin d2 induces cell deathThe specificity of proteasomes: impact on MHC class I processing and presentation of antigens.Biochemical characterization of deblocking aminopeptidases from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1.Proteasome inhibitors: from in vitro uses to clinical trials.Alternative endogenous protein processing via an autophagy-dependent pathway compensates for Yersinia-mediated inhibition of endosomal major histocompatibility complex class II antigen presentation.Pyrococcus horikoshii TET2 peptidase assembling process and associated functional regulation.Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation.A giant protease with a twist: the TPP II complex from Drosophila studied by electron microscopy.Integrated modeling of the major events in the MHC class I antigen processing pathway.Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells.Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress-associated apoptosis in HeLa cells.Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor.Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA.Voltage sensor mutations differentially target misfolded K+ channel subunits to proteasomal and non-proteasomal disposal pathways.Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivoMechanisms of MHC class I-restricted antigen presentation.No major role for insulin-degrading enzyme in antigen presentation by MHC molecules.Proteasome inhibition: a new anti-inflammatory strategy.
P2860
Q24541550-B82E8A86-BC50-4E42-97FF-838938CC527BQ24542503-EBF3F02A-744D-4875-A04C-23DF90FC318DQ24645843-9706F91B-7701-47A0-B07A-01E837A28EB2Q24669872-3AF330C0-4AB3-49D5-AACC-5851CFEE3406Q24679238-6CBDF78A-8BFB-4912-9DC5-50B049A55811Q26864074-DEBDFCD6-C4BC-494D-9475-3F4CB4470BDCQ26866479-520D826B-B492-424C-AF4E-C5BB095728B9Q27663767-EE1356E4-95D3-4748-9D96-4CBB6B19B8EBQ28181479-13C06151-A227-40EF-9A5E-BCA733B9D1F9Q28212341-9AAED16B-1EF6-4D7A-BBBF-E22756A2FE2EQ28214433-62960449-D571-44D2-B571-CB492F3380AAQ28367002-DB91AE1D-3765-4276-8480-C34913150B3DQ28541433-D3953C78-9370-47B5-8C4D-6F35E422C84EQ28582843-732B72A0-A151-4854-A420-AC63C384892DQ28593695-654DFFC8-2CF9-4583-A59B-AC9982C2F7EAQ30476037-51D0D94F-8D27-48B4-BFFB-73D984E15D35Q31026772-666299C9-8AB7-46DB-BB0B-65043A02598CQ33236277-46CE3D10-12CA-4E86-8B6C-5294B14D7833Q33275164-BFDE2879-4872-4899-B94F-2D9E6F182D50Q33418786-7FD28E20-0DBE-42F4-9B8F-3FF3DD81311FQ33591049-F18E8A0B-658B-411F-B5B3-3026CD93E57EQ33620219-BDC14DA9-DC72-4761-92A0-54ADC11C0BCAQ33761170-8C818CDB-BA0C-4D30-8898-7073C67A2BBAQ33815363-42E05C9F-1B1E-4A17-8890-770596CD5650Q33931677-2DB6C2A3-ACF1-4FE0-B147-4797855C7897Q34052405-F2206987-613B-442A-B761-B85B7262F41EQ34309646-90E199C2-9603-4D71-841D-EF2D606F8064Q34346058-D38B0A0C-429F-47F9-B387-DF3FDA54AFF1Q34362699-1D35BF32-6AFF-4068-B0B0-67CA5C2D2310Q34370046-DD0A271C-EE64-44F1-8700-70D303224D95Q34429970-8B76E33C-A7EE-4F90-BC52-AB85F68699FDQ34463706-6E2F6583-6D57-4B55-86C0-0FC97CD58481Q34540820-92D118CE-2006-498C-963C-35FCF0A7574AQ34789584-8CE08042-2563-4B14-A839-D79AFF2BA8DDQ34982271-212EF0A1-1F0C-4427-B0E2-906EB02D129FQ35006046-7CF0CF3D-6760-41DD-A315-2B0808334052Q35041080-7FFDE590-8A87-4374-9509-B867927E4FDDQ35050403-AA9EE166-7CB1-4603-8244-1C1BF616312BQ35091713-9DB2D592-F22E-4CFA-A967-766BCC9893A4Q35109750-58FAAA62-EECC-4F55-9CF3-2AB8C8B77655
P2860
A giant protease with potential to substitute for some functions of the proteasome
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A giant protease with potential to substitute for some functions of the proteasome
@ast
A giant protease with potential to substitute for some functions of the proteasome
@en
A giant protease with potential to substitute for some functions of the proteasome
@en-gb
A giant protease with potential to substitute for some functions of the proteasome
@nl
type
label
A giant protease with potential to substitute for some functions of the proteasome
@ast
A giant protease with potential to substitute for some functions of the proteasome
@en
A giant protease with potential to substitute for some functions of the proteasome
@en-gb
A giant protease with potential to substitute for some functions of the proteasome
@nl
prefLabel
A giant protease with potential to substitute for some functions of the proteasome
@ast
A giant protease with potential to substitute for some functions of the proteasome
@en
A giant protease with potential to substitute for some functions of the proteasome
@en-gb
A giant protease with potential to substitute for some functions of the proteasome
@nl
P2093
P2860
P1433
P1476
A giant protease with potential to substitute for some functions of the proteasome
@en
P2093
G Niedermann
K Eichmann
M Lucchiari-Hartz
W Baumeister
P2860
P304
P356
10.1126/SCIENCE.283.5404.978
P407
P577
1999-02-12T00:00:00Z