Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization
about
cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesisDistinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cellsCharacterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesisRole of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulationGlutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblastsSubcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] clusterHuman iron-sulfur cluster assembly, cellular iron homeostasis, and diseaseA novel eukaryotic factor for cytosolic Fe-S cluster assemblyIron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster deliveryNuclear localization of yeast Nfs1p is required for cell survival.Role of Saccharomyces cerevisiae ISA1 and ISA2 in iron homeostasisDual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55.J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins.Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution.Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs.The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteinsMouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesisMolecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone familyAlternative translation initiation augments the human mitochondrial proteomeRNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cellsNifS-directed assembly of a transient [2Fe-2S] cluster within the NifU proteinA Glutaredoxin-BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly MachineryClonal proteomics: one gene - family of proteins.Functions and cellular localization of cysteine desulfurase and selenocysteine lyase in Trypanosoma brucei.The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins.Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.A tribute to sulfur.Combinatorial mRNA regulation: iron regulatory proteins and iso-iron-responsive elements (Iso-IREs).Iron regulatory proteins in pathobiology.Cytosolic iron-sulfur cluster assembly (CIA) system: factors, mechanism, and relevance to cellular iron regulationConcise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biologyCompartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.Novel frataxin isoforms may contribute to the pathological mechanism of Friedreich ataxiaIron-sulfur cluster biogenesis and human diseaseThe L-cysteine desulfurase NFS1 is localized in the cytosol where it provides the sulfur for molybdenum cofactor biosynthesis in humansBiogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease.HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.Tissue specificity of a human mitochondrial disease: differentiation-enhanced mis-splicing of the Fe-S scaffold gene ISCU renders patient cells more sensitive to oxidative stress in ISCU myopathy.
P2860
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P2860
Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@ast
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en-gb
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@nl
type
label
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@ast
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en-gb
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@nl
prefLabel
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@ast
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en-gb
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@nl
P1433
P1476
Targeting of a human iron-sulf ...... gh alternative AUG utilization
@en
P2093
P304
P356
10.1016/S1097-2765(00)80295-6
P407
P577
1998-12-01T00:00:00Z