A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway
about
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeletonPSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organizationThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonCharacterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamilyIdentification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK betaMitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinaseA novel GTP-binding protein hGBP3 interacts with NIK/HGKThe CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase.A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinaseThe STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesionAgonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingIntracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeletonYeast Rio1p is the founding member of a novel subfamily of protein serine kinases involved in the control of cell cycle progression.MAP4K4: an emerging therapeutic target in cancerTAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loopBMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6Hematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascadeInvolvement of hematopoietic progenitor kinase 1 in T cell receptor signalingNESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesisIdentification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinaseMAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes.Cloning and characterization of MST4, a novel Ste20-like kinase.Peripheral arterial occlusive disease: global gene expression analyses suggest a major role for immune and inflammatory responses.Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) gamma protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in cultured adipocytes.MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance.Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase.RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27.HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistanceAssociation of common genetic variants in the MAP4K4 locus with prediabetic traits in humans.An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARgamma, adipogenesis, and insulin-responsive hexose transportThe Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastomaA pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway.Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK).Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein.Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosisICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulationMitomycin C-treated dendritic cells inactivate autoreactive T cells: toward the development of a tolerogenic vaccine in autoimmune diseases.Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients.Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases
P2860
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P2860
A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
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1999年學術文章
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name
A novel human STE20-related pr ...... minal kinase signaling pathway
@ast
A novel human STE20-related pr ...... minal kinase signaling pathway
@en
A novel human STE20-related pr ...... minal kinase signaling pathway
@en-gb
A novel human STE20-related pr ...... minal kinase signaling pathway
@nl
type
label
A novel human STE20-related pr ...... minal kinase signaling pathway
@ast
A novel human STE20-related pr ...... minal kinase signaling pathway
@en
A novel human STE20-related pr ...... minal kinase signaling pathway
@en-gb
A novel human STE20-related pr ...... minal kinase signaling pathway
@nl
prefLabel
A novel human STE20-related pr ...... minal kinase signaling pathway
@ast
A novel human STE20-related pr ...... minal kinase signaling pathway
@en
A novel human STE20-related pr ...... minal kinase signaling pathway
@en-gb
A novel human STE20-related pr ...... minal kinase signaling pathway
@nl
P2093
P2860
P3181
P356
P1476
A novel human STE20-related pr ...... minal kinase signaling pathway
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.4.2118
P407
P577
1999-01-22T00:00:00Z