Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionThe distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses.OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesTransport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).Characterization and identification of steroid sulfate transporters of human placentaCharge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutaminePharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Short-term regulation of organic anion transportersXenobiotic, bile acid, and cholesterol transporters: function and regulation.Structure of renal organic anion and cation transporters.Drug delivery across the blood-brain barrier: why is it difficult? how to measure and improve it?The organic anion transporter family: from physiology to ontogeny and the clinic.The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule.The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.Mechanisms and clinical implications of renal drug excretion.Structure, function, and regulation of renal organic anion transporters.Molecular and cellular physiology of renal organic cation and anion transport.Introduction of Organic Anion Transporters (SLC22A) and a Regulatory Mechanism by CaveolinsSLC22 transporter family proteins as targets for cytostatic uptake into tumor cells.Renal transport of organic anions and cations.Renal Drug Transporters and Drug Interactions.Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic influx and that are dysregulated in disease.Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells.The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid.Interaction of the bioactive flavonol, icariin, with the essential human solute carrier transporters.Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles.Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition.Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.Identification of metabolites of [14C]zonampanel, an a-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, following intravenous infusion in healthy volunteers.Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human Solute Carrier transporters.OAT1-3 transport organic anions with antiport of dicarboxylic acidsHuman organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function.
P2860
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P2860
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@ast
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en-gb
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@nl
type
label
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@ast
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en-gb
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@nl
prefLabel
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@ast
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en-gb
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@nl
P2093
P921
P356
P1476
Molecular cloning and characte ...... transporters (hOAT1 and hOAT3)
@en
P2093
E J Holtzman
S M Grassl
W J Williams
P304
P356
10.1006/BBRC.1998.9978
P407
P577
1999-02-16T00:00:00Z