Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
about
Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortexThe Pafah1b complex interacts with the reelin receptor VLDLRHow neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortexSimilarities and differences in structure, expression, and functions of VLDLR and ApoER2The generation and function of soluble apoE receptors in the CNSIdentification of alternatively spliced Dab1 and Fyn isoforms in pigIdentification of a human follicular dendritic cell molecule that stimulates germinal center B cell growthIdentification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissueDelta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neuronsThe proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptorNormal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplificationDisabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptorGene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22.A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signalingReelin expression and glycosylation patterns are altered in Alzheimer's diseaseSynergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brainApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recyclingCongenital hypoplasia of the cerebellum: developmental causes and behavioral consequencesReceptor clustering is involved in Reelin signalingReelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deploymentThe involvement of Reelin in neurodevelopmental disorders.Regulation of protein tyrosine kinase signaling by substrate degradation during brain developmentA neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteinsActivated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cellsCrk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathwayThe Reelin signaling pathway promotes dendritic spine development in hippocampal neuronsThe N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neuronsReelin signaling antagonizes beta-amyloid at the synapseMutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humansReduction of Crk and CrkL expression blocks reelin-induced dendritogenesisThrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cellsThrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migrationCullin 5 regulates Dab1 protein levels and neuron positioning during cortical developmentLow density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassemblyReelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibodyStructure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomographyNeuroanatomical phenotypes in the reeler mouse
P2860
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P2860
Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@ast
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en-gb
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@nl
type
label
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@ast
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en-gb
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@nl
prefLabel
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@ast
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en-gb
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@nl
P2093
P921
P3181
P1433
P1476
Reeler/Disabled-like disruptio ...... L receptor and ApoE receptor 2
@en
P2093
J A Richardson
M Trommsdorff
R E Hammer
T Hiesberger
W Stockinger
P304
P3181
P356
10.1016/S0092-8674(00)80782-5
P407
P577
1999-06-01T00:00:00Z