Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines
about
Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signalingMPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 functionPromoting bone morphogenetic protein signaling through negative regulation of inhibitory SmadsHuman ESCRT-II complex and its role in human immunodeficiency virus type 1 releaseAn RNF11: Smurf2 complex mediates ubiquitination of the AMSH proteinMutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndromeThe MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationLoss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice.AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4AMSH is an endosome-associated ubiquitin isopeptidaseRelease of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 buddingJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.The business of deubiquitination - location, location, locationAutophagy-Related Deubiquitinating Enzymes Involved in Health and DiseaseKey role for ubiquitin protein modification in TGFβ signal transductionThe ESCRT machinery: from the plasma membrane to endosomes and back againMacrophage migration inhibitory factor of the parasitic nematode Trichinella spiralisStructural Basis for ESCRT-III CHMP3 Recruitment of AMSHStructural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different StabilityA deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPSTAM2, a new member of the STAM family, binding to the Janus kinasesThe C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motifRegulation of endocytic sorting by ESCRT-DUB-mediated deubiquitinationRegulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesArabidopsis ALIX is required for the endosomal localization of the deubiquitinating enzyme AMSH3.The ESCRT-III-interacting deubiquitinating enzyme AMSH3 is essential for degradation of ubiquitinated membrane proteins in Arabidopsis thaliana.High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activityThe deubiquitinating enzyme AMSH1 and the ESCRT-III subunit VPS2.1 are required for autophagic degradation in Arabidopsis.The Arabidopsis deubiquitinating enzyme AMSH3 interacts with ESCRT-III subunits and regulates their localization.The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodiesA global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarityDeubiquitylase, deSUMOylase, and deISGylase activity microarrays for assay of substrate preference and functional modifiersThe regulation of TGF-β/SMAD signaling by protein deubiquitination.VHS domain -- a longshoreman of vesicle lines.STAM/EAST/Hbp adapter proteins--integrators of signalling pathways.Versatile roles of k63-linked ubiquitin chains in trafficking.Epigenetic regulation of lncRNA connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranesA central role for the ring finger protein RNF11 in ubiquitin-mediated proteolysis via interactions with E2s and E3s.
P2860
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P2860
Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Possible involvement of a nove ...... sduction mediated by cytokines
@ast
Possible involvement of a nove ...... sduction mediated by cytokines
@en
Possible involvement of a nove ...... sduction mediated by cytokines
@en-gb
Possible involvement of a nove ...... sduction mediated by cytokines
@nl
type
label
Possible involvement of a nove ...... sduction mediated by cytokines
@ast
Possible involvement of a nove ...... sduction mediated by cytokines
@en
Possible involvement of a nove ...... sduction mediated by cytokines
@en-gb
Possible involvement of a nove ...... sduction mediated by cytokines
@nl
prefLabel
Possible involvement of a nove ...... sduction mediated by cytokines
@ast
Possible involvement of a nove ...... sduction mediated by cytokines
@en
Possible involvement of a nove ...... sduction mediated by cytokines
@en-gb
Possible involvement of a nove ...... sduction mediated by cytokines
@nl
P2093
P356
P1476
Possible involvement of a nove ...... sduction mediated by cytokines
@en
P2093
K Sugamura
T Takeshita
P304
P356
10.1074/JBC.274.27.19129
P407
P577
1999-07-02T00:00:00Z