Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies
about
Mutational screening of 10 genes in Chinese patients with microphthalmia and/or colobomaAn Updated Review on the Genetics of Primary Open Angle GlaucomaThe sine oculis homeobox (SIX) family of transcription factors as regulators of development and diseaseA genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucomaClassification and nomenclature of all human homeobox genes.RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.Direct transcriptional regulation of Six6 is controlled by SoxB1 binding to a remote forebrain enhancerA genome-wide association study of optic disc parameters.Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open-angle glaucoma.Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development.DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucomaGenetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population.Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem CellsEye development genes and known syndromesDual transcriptional activities of SIX proteins define their roles in normal and ectopic eye developmentEvolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains bordersQuantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axis.P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in GlaucomaIdentification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia.Sequence alterations in RX in patients with microphthalmia, anophthalmia, and coloboma.optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila.Sine oculis, a member of the SIX family of transcription factors, directs eye formationNovel dominant-negative mutation within the six domain of the conserved eye specification gene sine oculis inhibits eye development in Drosophila.The non-conserved C-terminal segments of Sine Oculis Homeobox (SIX) proteins confer functional specificity.Molecular genetics in glaucoma.Ophthalmic and systemic findings in interstitial deletions of chromosome 14q: a case feport and literature review.Genetics of primary open angle glaucoma.Conserved genetic pathways associated with microphthalmia, anophthalmia, and coloboma.Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling.Major review: Molecular genetics of primary open-angle glaucoma.Optix defines a neuroepithelial compartment in the optic lobe of the Drosophila brain.Adenohypophysis placodal precursors exhibit distinctive features within the rostral preplacodal ectoderm.Finding common protein interaction patterns across organisms.A new locus for autosomal dominant posterior polar cataract in Moroccan Jews maps to chromosome 14q22-23.Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain.Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age.Distinct cis-acting regions control six6 expression during eye field and optic cup stages of eye formation.
P2860
Q24650708-5996313B-FD70-40F9-8D5E-A8DD0E2309E9Q26774468-A269EB1F-76DE-46EF-A23D-4C28B67E3F42Q28752140-C0B2355A-2612-44A2-BCB8-6430EAB1A004Q28943372-65A5BA21-EE26-4052-A803-D01ACA640834Q30481102-B0E90B7A-B4E5-4178-A93C-33F649F79AB4Q30483747-413DA7A1-22D4-4F7D-91CB-30CDC238DD18Q30531281-86C26B73-6766-4945-AA54-2AEF53897768Q33563970-71853591-D566-4FB2-A0D3-22FFD3E5C408Q33604802-C3F0F864-1FA8-43E9-9AF4-DEEE883042FCQ33686107-C8772A4C-DF76-4B8D-8085-6DA1CA294CF1Q33906989-B332EBAA-6C12-4EC0-9AB7-6BB40B023640Q34116870-D987879C-0C54-4457-BE8D-12DB5156F0CCQ34741765-ABE63BD1-391B-4D52-BFAA-D40BF0CC472DQ35005896-E349982F-CFB0-4061-8C2F-F982F1C798A2Q35167651-1E869B40-1752-4C5D-B332-C92773FAA7CCQ35573283-12156770-290F-4C59-94AC-C73A5120D98AQ35741929-B7BA666E-A2C0-40D2-9819-794B440FB13DQ35764452-0DB42FC9-D8A3-412C-8716-B0E2FD688B9EQ35875191-A3F8288F-76B2-473D-8ADD-2C6A89D36A6DQ36288914-0E58CCA8-7E62-4E70-8858-D5F6C972BBB0Q36289322-3905C26C-C741-48C8-BFCF-4A692114B24CQ36509388-32E02853-9E0D-4BA6-8C2D-7FED44348DDBQ37066070-135D72F3-3498-467E-9859-EBD7C473C502Q37093062-F502F156-0C64-4FAA-8E02-FF4214193451Q37286019-05AB52CD-0EAC-4B26-8CF7-F156189E15F6Q37331620-12A513D1-1913-441F-80C4-E2F7871D12B9Q37334675-EBDC6165-F4B1-41EC-BE49-ED4AECD18393Q37922872-2BD2F6C9-8C38-47AE-B90D-31CDE69C7AA5Q38001030-14A495F0-6B14-4A9E-8448-F45E0E5F3BD8Q38164595-EE8D0C7B-5D34-4D9D-8EE2-FB7FEB640A3BQ38517281-ED1A637D-532F-4F84-BA9B-415B5F12BEA8Q38829843-54DE6EE9-06E2-497F-9D61-F1ED967D0F1AQ39303267-7C36A96E-2960-4E48-A31E-C80B41F8F0ECQ41874812-B7E910CF-9C8F-462F-AB7D-5AD050E1CCDCQ42777976-E3F760D0-3E54-499F-AC53-574D9DC44269Q43138940-73FE461E-9360-4D3D-9894-698C54DC1669Q43145771-025F1B3F-2B8C-45D9-B05B-C171A97A86E8Q43151621-BCE132FF-2D52-4C84-A068-069CC183C4E1Q46172936-279AA963-59EB-4919-BFF9-04B11BB37B8CQ46377672-48482ADC-9CE3-4720-B415-79270C709868
P2860
Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Genomic cloning and characteri ...... halmia and pituitary anomalies
@ast
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en-gb
Genomic cloning and characteri ...... halmia and pituitary anomalies
@nl
type
label
Genomic cloning and characteri ...... halmia and pituitary anomalies
@ast
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en-gb
Genomic cloning and characteri ...... halmia and pituitary anomalies
@nl
prefLabel
Genomic cloning and characteri ...... halmia and pituitary anomalies
@ast
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en-gb
Genomic cloning and characteri ...... halmia and pituitary anomalies
@nl
P2093
P50
P356
P1433
P1476
Genomic cloning and characteri ...... halmia and pituitary anomalies
@en
P2093
B Granadino
H G Brunner
I Fernaud-Espinosa
M E Gallardo
M J Seller
S Rodríguez de Córdoba
P356
10.1006/GENO.1999.5916
P407
P577
1999-10-01T00:00:00Z