Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension
about
Mast cell mediators: their differential release and the secretory pathways involvedUrokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22The multifaceted mast cell in inflammatory bowel diseaseImplantation Serine Proteinases heterodimerize and are critical in hatching and implantationCloning and characterization of a transmembrane-type serine protease from rat kidney, a new sodium channel activatorMouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patternsMutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors.Tryptase 4, a new member of the chromosome 17 family of mouse serine proteases.Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells.Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1)Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing.Involvement of mast cells in eosinophilic esophagitis.Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitisBiochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transMast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscleCa2+ waves initiate antigen-stimulated Ca2+ responses in mast cellsTissue-specific expression of mast cell granule serine proteinases and their role in inflammation in the lung and gut.Mast cell tryptases and chymases in inflammation and host defense.Potential effector and immunoregulatory functions of mast cells in mucosal immunity.Mast cell alpha and beta tryptases changed rapidly during primate speciation and evolved from gamma-like transmembrane peptidases in ancestral vertebratesApproaches for analyzing the roles of mast cells and their proteases in vivo.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity.Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense.Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.The heterogeneity of mast cell tryptase from human lung and skin.Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells.A novel serine protease predominately expressed in macrophages.Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas.Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice.Suppressor of cytokine signaling 1 regulates an endogenous inhibitor of a mast cell protease.Cigarette smoke extract-treated mast cells promote alveolar macrophage infiltration and polarization in experimental chronic obstructive pulmonary disease.Formation of enzymatically active, homotypic, and heterotypic tetramers of mouse mast cell tryptases. Dependence on a conserved Trp-rich domain on the surface.
P2860
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P2860
Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Identification of a new member ...... terminal hydrophobic extension
@ast
Identification of a new member ...... terminal hydrophobic extension
@en
Identification of a new member ...... terminal hydrophobic extension
@en-gb
Identification of a new member ...... terminal hydrophobic extension
@nl
type
label
Identification of a new member ...... terminal hydrophobic extension
@ast
Identification of a new member ...... terminal hydrophobic extension
@en
Identification of a new member ...... terminal hydrophobic extension
@en-gb
Identification of a new member ...... terminal hydrophobic extension
@nl
prefLabel
Identification of a new member ...... terminal hydrophobic extension
@ast
Identification of a new member ...... terminal hydrophobic extension
@en
Identification of a new member ...... terminal hydrophobic extension
@en-gb
Identification of a new member ...... terminal hydrophobic extension
@nl
P2093
P2860
P921
P356
P1476
Identification of a new member ...... terminal hydrophobic extension
@en
P2093
D S Friend
R L Stevens
S A Krilis
P2860
P304
30784-30793
P356
10.1074/JBC.274.43.30784
P407
P577
1999-10-01T00:00:00Z