A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
about
Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like proteinProtein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing.Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodiesC16orf57, a gene mutated in poikiloderma with neutropenia, encodes a putative phosphodiesterase responsible for the U6 snRNA 3' end modificationp110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factorA protein interaction framework for human mRNA degradationStructural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeHuman U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recyclingRecycling of the U12-type spliceosome requires p110, a component of the U6atac snRNPFunctional organization of the Sm core in the crystal structure of human U1 snRNPSystematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzymeMinor spliceosome components are predominantly localized in the nucleusUnique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processingRNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex.The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomesHierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteinsSMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like proteinProteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.The N- and C-terminal RNA recognition motifs of splicing factor Prp24 have distinct functions in U6 RNA bindingSymmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem regionA conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formationThe human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodiesSm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure.The Sm domain is an ancient RNA-binding motif with oligo(U) specificityA Sm-like protein complex that participates in mRNA degradationThe oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)Down-regulation of Lsm1 is involved in human prostate cancer progressionStructure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopyThe Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in developmentDetection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transferA role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayThe crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP coreCrystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukaryaHomomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA. Crystal structure of an oligomeric complex of yeast SmFStructure and assembly of an augmented Sm-like archaeal protein 14-merSm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coliCrystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 Å resolution
P2860
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P248
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P2860
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@ast
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en-gb
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@nl
type
label
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@ast
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en-gb
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@nl
prefLabel
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@ast
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en-gb
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@nl
P2093
P921
P356
P1433
P1476
A doughnut-shaped heteromer of ...... 4/U6 duplex formation in vitro
@en
P2093
P304
P356
10.1093/EMBOJ/18.20.5789
P407
P577
1999-10-01T00:00:00Z