Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
about
A functional and regulatory network associated with PIP expression in human breast cancerEph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesisThe EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent mannerIdentification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling functionKSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfateEphB1 associates with Grb7 and regulates cell migrationEphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with AktFAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapseHepatitis C virus infection protein networkReceptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migrationSoluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptorInhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPasesPTP1B regulates Eph receptor function and traffickingEphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxisRegulation of focal adhesion kinase by a novel protein inhibitor FIP200The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesionQuantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC)Structural basis for the autoinhibition of focal adhesion kinaseDifferential regulation of EphA2 in normal and malignant cellsExpression and functional effects of Eph receptor tyrosine kinase A family members on Langerhans like dendritic cellsEphA receptor signaling--complexity and emerging themesEphs and ephrins in cancer: ephrin-A1 signallingEphrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's diseasePharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansionAn extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylationThe ephrin signaling pathway regulates morphology and adhesion of mouse granulosa cells in vitroSignals from Eph and ephrin proteins: a developmental tool kitActivation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascadeMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorCharacterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissuesRegulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformationCell-specific information processing in segregating populations of Eph receptor ephrin-expressing cellsEpidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinaseA novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasionLithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activationThe synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathwayVariable metastatic potentials correlate with differential plectin and vimentin expression in syngeneic androgen independent prostate cancer cellsExpression of Eph receptors and their ligands, ephrins, during lipopolysaccharide fever in ratsRegulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1
P2860
06b9a712463ecdda2f8aeca8131106b56369e3462f724323d511bb80566a4e5bb23d51dd0f79a1bd44e7813d22274a1c688f6fa4dd4f9199046f6b2753808b13efb452916f1c8768b1bf492b36ae1f7173974d730efe2716f251cecd5791b8c05b81458d8a5c99c100c51bec19735458b75c0e8e0505df2a97e79f3727162089ce43a2513f9e0cbc756713d79926283c468aa36760ecac86e2837d363bdabf1e9cd6269a6ff2c085821f5e169e8e83c16fc00439a42e4ce1c24f628e48c82090c140f669c69dcf73edbc5da413d32a2eb06c7e36314a10c47948e9f8
P248
Q21143857-A0952319-9FD9-49B8-A1A1-812BD7AAB41DQ21328694-5E4AD024-ABD9-452D-97D3-32950142D592Q24291347-9A5F10BF-799B-40CD-A036-4125229B83CAQ24294195-23DC32AC-93F0-4C1E-AC22-A55385C586EDQ24301376-A916A981-81C3-46C7-B5CF-7D3616EBC70BQ24306491-A9A119F6-8D5C-4CF9-9732-4CD52A7B8477Q24310260-5FBEB347-1AD5-4A16-925B-4C7F74816DF7Q24310437-B87EAD65-9EBD-4747-A0D5-31236AE7030CQ24311906-4799F5A1-51CD-4053-9FE6-FE5314A4C820Q24312704-400B242E-09FB-4816-992F-B98F55787173Q24313139-C1D771B4-523F-469C-962A-DC204A82AEC9Q24313265-FCFAC558-301D-4875-BFA3-6293DD2D238DQ24313351-EBD3F95B-1808-4361-AFA6-A8B4F18565D6Q24316344-7A09D934-21EB-47BD-A51C-F308CBA9E182Q24530047-A4B35454-CFEB-4616-B4DA-4445FBB1971EQ24550570-E0C1A81D-EE55-47C4-A82E-D554AB662202Q24648024-17C58654-3506-4065-9D13-FA47C634879EQ24678318-B01B41A7-8E5D-4986-BCB3-54BE6AC1BBF2Q24684095-7AF7D0CA-2556-4FB8-A622-F1241D06C8DCQ24799713-E86B9DA2-7417-4275-B769-C2C9BC71C9D5Q26864082-F2659489-C55A-4328-B70D-D9BC4212E134Q26864889-0D7DB418-5AE7-4254-A6E8-CB94A0D27327Q27308757-4BBBCF9B-4408-4B81-9D35-A69DB9EFD0BFQ27310708-3AB8F6EC-2D86-493C-9400-F6E06F294A33Q27660230-9A71989F-205A-4BCD-B21A-4C4A484AE1EDQ28116202-6AFB1938-DA41-4145-B13A-C8C0CF571E26Q28117197-552E9FB4-5AE9-418D-98A5-8E63419AFC21Q28210262-67D29C41-463C-43D0-9346-2F7142CB460BQ28210840-AF8E3A22-63D7-4F50-B41C-29C4513D4FD0Q28211704-AB5F8786-E249-449B-8921-A704B7FA16BBQ28214281-6551A94F-CCC2-4490-83BA-DD71F4C328BCQ28217169-39C5986C-D039-4830-8DC5-69E53DC80D4EQ28267574-A4C0D3F8-750F-449D-BFB4-480DE0EA9ECAQ28365466-817F5B41-4979-4592-8117-E5B71C20725BQ28477362-E736B25F-D412-4594-BE57-60F44B02543CQ28477562-E32C49D5-393A-4730-A306-7BEEE8EEED21Q28507076-803B190A-06A8-4D85-AB9B-63328E162111Q28533234-48B2CCDA-629E-4E4F-9F0E-AE7A4966F9A1Q28574469-29C80071-EBA7-4475-B683-A4FBE4B4740DQ28585388-3C9B917E-DECE-4444-9DDE-D48A321721D0
P2860
Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@ast
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en-gb
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@nl
type
label
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@ast
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en-gb
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@nl
prefLabel
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@ast
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en-gb
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Activation of EphA2 kinase sup ...... esion-kinase dephosphorylation
@en
P2093
P2860
P2888
P3181
P356
10.1038/35000008
P407
P577
2000-02-01T00:00:00Z
P5875
P6179
1045980134