The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans
about
P1343
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in LeishmaniaFormation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1Trypanosoma brucei brucei: thymine 7-hydroxylase-like proteins.Identification of the glucosyltransferase that converts hydroxymethyluracil to base J in the trypanosomatid genome.Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.Quantitative mass spectrometry-based analysis of β-D-glucosyl-5-hydroxymethyluracil in genomic DNA of Trypanosoma brucei.Epigenetic regulation of transcription and virulence in Trypanosoma cruzi by O-linked thymine glucosylation of DNA.Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.JBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNABase J glucosyltransferase does not regulate the sequence specificity of J synthesis in trypanosomatid telomeric DNA.Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite Entamoeba histolytica.JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomesRecognition of base J in duplex DNA by J-binding protein.Telomere maintenance and length regulation in Trypanosoma brucei.Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania.J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.JBP2, a SWI2/SNF2-like protein, regulates de novo telomeric DNA glycosylation in bloodstream form Trypanosoma brucei.Fe(II)/alpha-ketoglutarate hydroxylases involved in nucleobase, nucleoside, nucleotide, and chromatin metabolism.The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads.
P2860
Q24611470-EAE15372-CD79-48C8-B3DB-C5BB59D06ACDQ24804738-44B9A1D2-DA9D-4861-A2EF-C1C9F508AD7BQ27667282-8DFED5AA-8F6F-4B3D-9378-D3F5278B8E24Q33665483-8A0C627E-02C1-49C7-84E3-6AD5D0EF9DBEQ33931238-42C77E33-3464-40AC-900D-70AD6A5D7767Q33959441-6E3E7BE4-C7D4-43C2-88E1-146C5651B398Q34175560-DAAAC0BB-6D39-4664-8D8E-71934DD76F84Q35077113-49B12FEC-48B2-4CAD-8F3E-3F5DB034F098Q35131187-C500A8C6-2226-4B16-86DA-DB6F800FCF6DQ36016773-3F0FA02C-9E84-4930-BF73-D91169F6A643Q36956570-DA2E4740-6404-4FE7-8977-8B4F14A67102Q37067895-68BB01FD-53C4-4DBE-A647-508597BBCB3DQ37128117-5D94467B-9A57-497E-B065-047C0BB6D485Q38294915-57579EEA-2996-4ADF-BEE2-910A504008E8Q39077195-D5B1F1AC-9406-4C4A-A8F6-6178919002F7Q39687136-42D77390-4681-45FA-B826-65898FBFE099Q41857586-B284BFAE-BA8A-4049-84CF-7C3827911300Q42254040-7E4AA1C2-6B46-4D19-B222-5A77A10DB3EBQ42526672-2CE7BF8D-ABF3-4D2E-B2F0-4CC393204539Q42541455-03FD49E9-0B9A-4969-887C-18489F9642E5Q42719732-4924D353-4BC1-42AF-A98F-28B3F22CF896Q42779807-90B13A93-433E-4C7D-B9EC-D1169AD2748BQ44005236-F9744873-5C63-4712-B041-CC5407B179EDQ54343517-ECAA4BED-D657-4D8F-A7D9-7F3426515E1C
P2860
The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The modified base J is the tar ...... in in kinetoplastid protozoans
@ast
The modified base J is the tar ...... in in kinetoplastid protozoans
@en
The modified base J is the tar ...... in in kinetoplastid protozoans
@en-gb
The modified base J is the tar ...... in in kinetoplastid protozoans
@nl
type
label
The modified base J is the tar ...... in in kinetoplastid protozoans
@ast
The modified base J is the tar ...... in in kinetoplastid protozoans
@en
The modified base J is the tar ...... in in kinetoplastid protozoans
@en-gb
The modified base J is the tar ...... in in kinetoplastid protozoans
@nl
prefLabel
The modified base J is the tar ...... in in kinetoplastid protozoans
@ast
The modified base J is the tar ...... in in kinetoplastid protozoans
@en
The modified base J is the tar ...... in in kinetoplastid protozoans
@en-gb
The modified base J is the tar ...... in in kinetoplastid protozoans
@nl
P2093
P356
P1433
P1476
The modified base J is the tar ...... in in kinetoplastid protozoans
@en
P2093
Sabatini R
van Boom JH
van der Marel GA
P304
P356
10.1093/EMBOJ/18.22.6573
P407
P577
1999-11-01T00:00:00Z