A novel transcription factor, T-bet, directs Th1 lineage commitment
about
Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesoderminExosomes as a tumor immune escape mechanism: possible therapeutic implicationsThe T-box familyDefects in mucosal immunity leading to Crohn's diseaseMHC class II transactivator represses human IL-4 gene transcription by interruption of promoter binding with CBP/p300, STAT6 and NFAT1 via histone hypoacetylationPlasma cell differentiation requires the transcription factor XBP-1Differential expression of CD300a/c on human TH1 and TH17 cellsThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genesJanus kinases in immune cell signalingT-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) speciesTxk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsGATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical modelMedical immunology: a new journal for a new subspecialty.NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expressionT-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-siteTBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroidsThe transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathwayIL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanismsThe lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patternsFollicular helper T cells in immunity and systemic autoimmunityMolecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signalingThe role of NKT cells in tumor immunityT-bet polymorphisms are associated with asthma and airway hyperresponsivenessThe BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functionsGlobal mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cellsInterleukin 18 and associated markers of T helper cell type 1 activity in coeliac diseaseCD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferationInterleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cellsExpression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomasSchnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cellsInteraction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytesAPC-derived cytokines and T cell polarization in autoimmune inflammationAlteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cellsDistinct gene expression profiles of human type 1 and type 2 T helper cellsMicroarray profiling of lymphocytes in internal diseases with an altered immune response: potential and methodologyEpigenetics and inheritance of phenotype variation in livestockThe Mucosal Immune System and Its Regulation by AutophagyT-bet and Eomesodermin in NK Cell Development, Maturation, and FunctionRegulation of the Adaptive Immune Response by the IκB Family Protein Bcl-3TCR Signaling in T Cell Memory
P2860
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P2860
A novel transcription factor, T-bet, directs Th1 lineage commitment
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
A novel transcription factor, T-bet, directs Th1 lineage commitment
@ast
A novel transcription factor, T-bet, directs Th1 lineage commitment
@en
A novel transcription factor, T-bet, directs Th1 lineage commitment
@nl
type
label
A novel transcription factor, T-bet, directs Th1 lineage commitment
@ast
A novel transcription factor, T-bet, directs Th1 lineage commitment
@en
A novel transcription factor, T-bet, directs Th1 lineage commitment
@nl
prefLabel
A novel transcription factor, T-bet, directs Th1 lineage commitment
@ast
A novel transcription factor, T-bet, directs Th1 lineage commitment
@en
A novel transcription factor, T-bet, directs Th1 lineage commitment
@nl
P2093
P3181
P1433
P1476
A novel transcription factor, T-bet, directs Th1 lineage commitment
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)80702-3
P407
P577
2000-03-17T00:00:00Z