The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells
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LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosisEvolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathwaySoluble receptor (DcR3) and cellular inhibitor of apoptosis-2 (cIAP-2) protect human cytotrophoblast cells against LIGHT-mediated apoptosisThe regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHTModulation of T-cell responses to alloantigens by TR6/DcR3Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranesTargeting and utilizing primary tumors as live vaccines: changing strategiesStructurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signalingBiochemical and Structural Characterization of the Human TL1A Ectodomain ,Decoy Strategies: The Structure of TL1A:DcR3 ComplexMechanistic Basis for Functional Promiscuity in the TNF and TNF Receptor Superfamilies: Structure of the LIGHT:DcR3 AssemblyHVEM signalling at mucosal barriers provides host defence against pathogenic bacteriaAxl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma.TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling.Excess LIGHT contributes to placental impairment, increased secretion of vasoactive factors, hypertension, and proteinuria in preeclampsia.The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses.Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins.T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment.Localization of the gD-binding region of the human herpes simplex virus receptor, HveAExpression of LIGHT/TNFSF14 combined with vaccination against human papillomavirus Type 16 E7 induces significant tumor regressionAllosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.The LIGHT and DARC sides of herpesvirus entry mediatorPolymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability.Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competitionCation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein.Survey of the year 2000 commercial optical biosensor literature.Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis.Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signalingCloning, expression, and characterization of TNFSF14 (LIGHT) gene in mefugu, Takifugu obscurus.IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease.Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.TNF Superfamily Networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14)Death Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis.Tumor-specific T cells signal tumor destruction via the lymphotoxin beta receptorCD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING.Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.NK-cell activation by LIGHT triggers tumor-specific CD8+ T-cell immunity to reject established tumorsThe role of coinhibitory signaling pathways in transplantation and toleranceThe signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation
P2860
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P2860
The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
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name
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@ast
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en-gb
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@nl
type
label
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@ast
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en-gb
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@nl
prefLabel
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@ast
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en-gb
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@nl
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P2860
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P1476
The lymphotoxin-beta receptor ...... iated apoptosis of tumor cells
@en
P2093
C A Benedict
I A Rooney
J C Whitbeck
K D Butrovich
R J Eisenberg
S Borboroglu
P2860
P304
P3181
P356
10.1074/JBC.275.19.14307
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P577
2000-05-12T00:00:00Z