Gli regulation by the opposing activities of fused and suppressor of fused
about
The FU gene and its possible protein isoformsDual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentThe negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteinsSuppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complexMIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcriptionSuppressor of fused regulates Gli activity through a dual binding mechanismThe zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesisA possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulationSuppressor of fused negatively regulates beta-catenin signalingStructural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancerGLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functionsIdentification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functionsLoss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalusCoordinated translocation of mammalian Gli proteins and suppressor of fused to the primary ciliumGLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.Mechanism and evolution of cytosolic Hedgehog signal transductionDifferential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling.Regulation of Hedgehog signaling: a complex story.The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Mutational analysis of hedgehog signaling pathway genes in human malignant mesotheliomaVariant allele frequency enrichment analysis in vitro reveals sonic hedgehog pathway to impede sustained temozolomide response in GBMT396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressorLentivirus-mediated SMO RNA interference inhibits SMO expression and cell proliferation, and affects the cell cycle in LNCaP and PC3 cancer cell lines.Medulloblastoma: what is the role of molecular genetics?An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling.Mechanisms of Hedgehog signalling in cancer.Crosstalk between TGF-β and hedgehog signaling in cancer.The role of hedgehog signalling in skeletal health and disease.Targeting the hedgehog signaling pathway for cardiac repair and regeneration.No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours.The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells.Diversity, classification and function of the plant protein kinase superfamily.Suppressor of fused (Sufu) mediates the effect of parathyroid hormone-like hormone (Pthlh) on chondrocyte differentiation in the growth plate.Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling.
P2860
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P248
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P2860
Gli regulation by the opposing activities of fused and suppressor of fused
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Gli regulation by the opposing activities of fused and suppressor of fused
@ast
Gli regulation by the opposing activities of fused and suppressor of fused
@en
Gli regulation by the opposing activities of fused and suppressor of fused
@en-gb
Gli regulation by the opposing activities of fused and suppressor of fused
@nl
type
label
Gli regulation by the opposing activities of fused and suppressor of fused
@ast
Gli regulation by the opposing activities of fused and suppressor of fused
@en
Gli regulation by the opposing activities of fused and suppressor of fused
@en-gb
Gli regulation by the opposing activities of fused and suppressor of fused
@nl
prefLabel
Gli regulation by the opposing activities of fused and suppressor of fused
@ast
Gli regulation by the opposing activities of fused and suppressor of fused
@en
Gli regulation by the opposing activities of fused and suppressor of fused
@en-gb
Gli regulation by the opposing activities of fused and suppressor of fused
@nl
P2093
P2860
P921
P356
P1433
P1476
Gli regulation by the opposing activities of fused and suppressor of fused
@en
P2093
A Rosenthal
F J de Sauvage
M Armanini
P2860
P2888
P356
10.1038/35010610
P407
P577
2000-05-01T00:00:00Z
P6179
1042245654