Evolution of sodium channels predates the origin of nervous systems in animals - Test2 - elhamkhani - TriplyDB

Evolution of sodium channels predates the origin of nervous systems in animals

Evolution of sodium channels predates the origin of nervous systems in animals

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The genome of the ctenophore Mnemiopsis leidyi and its implications for cell type evolution The ctenophore genome and the evolutionary origins of neural systems.Adaptive evolution of voltage-gated sodium channels: the first 800 million years Complex Homology and the Evolution of Nervous Systems From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes Gastric pouches and the mucociliary sole: setting the stage for nervous system evolution The evolution of early neurogenesis Quantitative description of ion transport via plasma membrane of yeast and small cells Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress Convergent evolution of neural systems in ctenophores Moving and sensing without input and output: early nervous systems and the origins of the animal sensorimotor organization A tale of two drug targets: the evolutionary history of BACE1 and BACE2 Convergent evolution of sodium ion selectivity in metazoan neuronal signaling Gene transcription and splicing of T-type channels are evolutionarily-conserved strategies for regulating channel expression and gating Parallel evolution of tetrodotoxin resistance in three voltage-gated sodium channel genes in the garter snake Thamnophis sirtalis.A uniquely adaptable pore is consistent with NALCN being an ion sensor Evolutionary insights into premetazoan functions of the neuronal protein homer.Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels.Convergence of ion channel genome content in early animal evolution.Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view Evolution of sodium channels and the new view of early nervous system evolution.Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage-insensitive clade.Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4 What makes a sodium channel?Physiology and Evolution of Voltage-Gated Calcium Channels in Early Diverging Animal Phyla: Cnidaria, Placozoa, Porifera and Ctenophora.Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation.Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas.T-type channels become highly permeable to sodium ions using an alternative extracellular turret region (S5-P) outside the selectivity filter.Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity.Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels.Physiological inputs regulate species-specific anatomy during embryogenesis and regeneration.Small molecule modulation of voltage gated sodium channels.Evolution of the cation chloride cotransporter family: ancient origins, gene losses, and subfunctionalization through duplication.The evolution of the four subunits of voltage-gated calcium channels: ancient roots, increasing complexity, and multiple losses.Guanidinium Toxins and Their Interactions with Voltage-Gated Sodium Ion Channels.Calmodulin regulates Cav3 T-type channels at their gating brake.Conspicuousness, color resemblance, and toxicity in geographically diverging mimicry: The pan-Amazonian frog Allobates femoralis.A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating.Ecological constraints on the origin of neurones.Voltage-gated sodium channels assemble and gate as dimers.

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Evolution of sodium channels predates the origin of nervous systems in animals

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Evolution of sodium channels predates the origin of nervous systems in animals

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Evolution of sodium channels predates the origin of nervous systems in animals

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Evolution of sodium channels predates the origin of nervous systems in animals

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Proceedings of the National Academy of Sciences of the United States of America

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Evolution of sodium channels predates the origin of nervous systems in animals

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Benjamin J Liebeskind

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David M Hillis

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Harold H Zakon

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P2860

Resolving difficult phylogenetic questions: why more sequences are not enough

The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans

Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates

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The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

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Molecular signatures for sex in the Placozoa

MAFFT version 5: improvement in accuracy of multiple sequence alignment

Molecular phylogeny of choanoflagellates, the sister group to Metazoa

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