Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
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Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neuronsChronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamineInactivation of Pde8b enhances memory, motor performance, and protects against age-induced motor coordination decay.Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.Evaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverinePhosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical ImplicationsCurrent status of PET imaging in Huntington's diseaseThe role of ventral striatal cAMP signaling in stress-induced behaviors.Efficacy of selective PDE4D negative allosteric modulators in the object retrieval task in female cynomolgus monkeys (Macaca fascicularis)HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?Differential changes in amygdala and frontal cortex Pde10a expression during acute and protracted withdrawalA new model of Pde4d deficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects.TAK-063, a PDE10A Inhibitor with Balanced Activation of Direct and Indirect Pathways, Provides Potent Antipsychotic-Like Effects in Multiple ParadigmsInhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating.Striatal neurones have a specific ability to respond to phasic dopamine releasePhosphodiesterase 10A regulates alcohol and saccharin self-administration in ratsRACK1 and β-arrestin2 attenuate dimerization of PDE4 cAMP phosphodiesterase PDE4D5Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brainInhibition of Phosphodiesterase 10A Increases the Responsiveness of Striatal Projection Neurons to Cortical StimulationRadiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primateThe phosphodiesterase-4 (PDE4) inhibitor rolipram decreases ethanol seeking and consumption in alcohol-preferring Fawn-Hooded ratsRole of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine IntegrationERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertionDendritic geometry shapes neuronal cAMP signalling to the nucleusEffects of a novel phosphodiesterase 10A inhibitor in non-human primates: A therapeutic approach for schizophrenia with improved side effect profileToxoplasma gondii Infection in Mice Impairs Long-Term Fear Memory Consolidation through Dysfunction of the Cortex and Amygdala.Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3)Comparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primatesPrenatal environmental exposures, epigenetics, and diseaseCross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingCalcium-dependent inactivation of calcium channels in the medial striatum increases at eye openingAutophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in StriatumDISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessAcupuncture enhances the synaptic dopamine availability to improve motor function in a mouse model of Parkinson's diseaseThe internal state of medium spiny neurons varies in response to different input signalsPhosphodiesterase regulation of alcohol drinking in rodents.Review: Modulation of striatal neuron activity by cyclic nucleotide signaling and phosphodiesterase inhibitionRole of adrenoceptors in the regulation of dopamine/DARPP-32 signaling in neostriatal neurons.Segregation and crosstalk of D1 receptor-mediated activation of ERK in striatal medium spiny neurons upon acute administration of psychostimulants
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P2860
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@ast
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en-gb
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@nl
type
label
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@ast
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en-gb
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@nl
prefLabel
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@ast
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en-gb
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@nl
P2093
P2860
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Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
@en
P2093
Akinori Nishi
Gretchen L Snyder
Helen S Bateup
Mahomi Kuroiwa
Naoki Sotogaku
Nathaniel Heintz
Takahide Shuto
Takaichi Fukuda
P2860
P2880
P304
P3181
P356
10.1523/JNEUROSCI.2518-08.2008
P407
P577
2008-10-15T00:00:00Z