Human inter-individual variability in metabolism and genotoxic response to zidovudine - Test2 - elhamkhani - TriplyDB

Human inter-individual variability in metabolism and genotoxic response to zidovudine

Human inter-individual variability in metabolism and genotoxic response to zidovudine

http://www.wikidata.org/entity/Q23918962

about

Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells Effects of Zidovudine Treatment on Heart mRNA Expression and Mitochondrial DNA Copy Number Associated with Alterations in Deoxynucleoside Triphosphate Composition in a Neonatal Rat Model In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells

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P2860

Human inter-individual variability in metabolism and genotoxic response to zidovudine

http://www.wikidata.org/entity/Q23918962

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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prefLabel

Human inter-individual variability in metabolism and genotoxic response to zidovudine

@ast

Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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J.TAAP.2007.12.005

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Toxicology and Applied Pharmacology

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Human inter-individual variability in metabolism and genotoxic response to zidovudine

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Diana L Richardson

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Irma L Vazquez

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Jessica M Ming

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Miriam C Poirier

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Ofelia A Olivero

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Shreyasi Das

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P2860

Transcriptional signatures of environmentally relevant exposures in normal human mammary epithelial cells: benzo(a)pyrene

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

Pharmacologic considerations for therapeutic success with antiretroviral agents.

A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group.

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.

Host factors and efficacy of antiretroviral treatment.

Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors.

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

A second useful polymorphism for the cytosolic thymidine kinase gene (TK1) with the enzyme BstEII which will allow haplotying at this locus on chromosome 17 (q21-q22).

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20033865

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2

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228

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5645817

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18206198

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National Institute for Occupational Safety and Health

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exposure assessment

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2384225

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