An open investigation of the reproducibility of cancer biology research
about
Reproducible Research Practices and Transparency across the Biomedical LiteratureReplication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumorsReplication Study: Melanoma genome sequencing reveals frequent PREX2 mutationsReplication Study: BET bromodomain inhibition as a therapeutic strategy to target c-MycReplication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression dataReplication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugsMaking sense of replicationsRegistered report: Systematic identification of genomic markers of drug sensitivity in cancer cellsRegistered report: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through METRegistered Report: COT drives resistance to RAF inhibition through MAP kinase pathway reactivationRegistered report: IDH mutation impairs histone demethylation and results in a block to cell differentiationRegistered report: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAsRegistered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarateRegistered report: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulationsRegistered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAFRegistered report: Diverse somatic mutation patterns and pathway alterations in human cancersRegistered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growthRegistered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinomaRegistered report: A coding-independent function of gene and pseudogene mRNAs regulates tumour biologyRegistered report: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukemiaRegistered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironmentAssessing the reproducibility of discriminant function analyses.Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenasesRegistered report: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasisTime to do something about reproducibilityEstimating the reproducibility of psychological scienceThe Bitter Truth About Sugar and Willpower: The Limited Evidential Value of the Glucose Model of Ego Depletion.Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.Can cancer researchers accurately judge whether preclinical reports will reproduce?Overflow in science and its implications for trust.RIPOSTE: a framework for improving the design and analysis of laboratory-based research.Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.Training to Improve Precision and Accuracy in the Measurement of Fiber Morphology.Publication bias and the canonization of false facts.Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era.Talking the talk, but not walking the walk: RT-qPCR as a paradigm for the lack of reproducibility in molecular research.Validation of Molecular Simulation: An Overview of Issues.Common pitfalls in preclinical cancer target validation.Class-paired Fuzzy SubNETs: A paired variant of the rank-based network analysis family for feature selection based on protein complexes.
P2860
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P2860
An open investigation of the reproducibility of cancer biology research
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
An open investigation of the reproducibility of cancer biology research
@ast
An open investigation of the reproducibility of cancer biology research
@en
An open investigation of the reproducibility of cancer biology research
@en-gb
An open investigation of the reproducibility of cancer biology research
@nl
type
label
An open investigation of the reproducibility of cancer biology research
@ast
An open investigation of the reproducibility of cancer biology research
@en
An open investigation of the reproducibility of cancer biology research
@en-gb
An open investigation of the reproducibility of cancer biology research
@nl
prefLabel
An open investigation of the reproducibility of cancer biology research
@ast
An open investigation of the reproducibility of cancer biology research
@en
An open investigation of the reproducibility of cancer biology research
@en-gb
An open investigation of the reproducibility of cancer biology research
@nl
P2860
P50
P3181
P356
P1433
P1476
An open investigation of the reproducibility of cancer biology research
@en
P2093
Fraser Elisabeth Tan
William Gunn
P2860
P3181
P356
10.7554/ELIFE.04333
P407
P577
2014-12-10T00:00:00Z