A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z' Factor, and Assay Variability Ratio
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The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection ModelHit selection with false discovery rate control in genome-scale RNAi screensAssay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid CulturesHigh-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonaseIntegrating experimental and analytic approaches to improve data quality in genome-wide RNAi screensAlternative statistical parameter for high-throughput screening assay quality assessmentNovel analytic criteria and effective plate designs for quality control in genome-scale RNAi screensHigh throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinaseImplementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathwayFunctional coupling of a nematode chemoreceptor to the yeast pheromone response pathwayEstablishment of a High-Throughput Assay to Monitor Influenza A Virus RNA Transcription and ReplicationDevelopment of a high-throughput colorimetric Zika virus infection assayMultiparametric Analysis of Screening Data: Growing Beyond the Single Dimension to Infinity and Beyond.A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assayHigh-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db miceDiscovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assayFrom cosubstrate similarity to inhibitor diversity--inhibitors of ADP-ribosyltransferases from kinase inhibitor screening.Homogeneous screening assay for human tankyrase.Target assessment for antiparasitic drug discovery.A high-throughput assay to identify small-molecule modulators of alternative pre-mRNA splicing.Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors.5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.Whole-organism high-throughput screening against Trypanosoma brucei brucei.Small-molecule collection and high-throughput colorimetric assay to identify PARP1 inhibitors.Microplate-based assay for identifying small molecules that bind a specific intersubunit interface within the assembled HIV-1 capsid.A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabAStatistical Evaluation of HTS Assays for Enzymatic Hydrolysis of β-Keto Esters.Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds.High-throughput screening using the differential radial capillary action of ligand assay identifies ebselen as an inhibitor of diguanylate cyclases.A cell-based high-throughput approach to identify inhibitors of influenza A virus.Design and implementation of high throughput screening assays.Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for development of antiviral agents.A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image AnalysisOpen Source High Content Analysis Utilizing Automated Fluorescence Lifetime Imaging Microscopy.Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.Multiparametric cell-based assay for the evaluation of transcription inhibition by high-content imaging.An automated high-content screening image analysis pipeline for the identification of selective autophagic inducers in human cancer cell lines.ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum.Identification of a specific agonist of human TAS2R14 from Radix Bupleuri through virtual screening, functional evaluation and binding studies.
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P2860
A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z' Factor, and Assay Variability Ratio
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2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@ast
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en-gb
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
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type
label
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@ast
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en-gb
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@nl
altLabel
A comparison of assay performa ...... r, and assay variability ratio
@en
prefLabel
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@ast
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@en-gb
A Comparison of Assay Performa ...... r, and Assay Variability Ratio
@nl
P2860
P3181
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A Comparison of Assay Performa ...... r, and Assay Variability Ratio
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P2093
P. W. Iversen
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P304
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10.1177/1087057105285610
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P577
2006-02-20T00:00:00Z