Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala - Test2 - elhamkhani - TriplyDB

Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala

Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala

http://www.wikidata.org/entity/Q24289260

about

Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders Candidate gene-environment interaction research: reflections and recommendations.Identifying genetic variation for alcohol dependence A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.Mechanisms of neuroimmune gene induction in alcoholism High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism.CRF-amplified neuronal TLR4/MCP-1 signaling regulates alcohol self-administration.MicroRNAs in addiction: adaptation's middlemen?Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation Toll-like receptor signaling and stages of addiction.The Genetics, Neurogenetics and Pharmacogenetics of Addiction Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala.Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain.Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics.Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system.Tigecycline Reduces Ethanol Intake in Dependent and Nondependent Male and Female C57BL/6J Mice.Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence Release of neuronal HMGB1 by ethanol through decreased HDAC activity activates brain neuroimmune signaling.Fetal alcohol spectrum disorders and neuroimmune changes Binge Drinking: In Search of its Molecular Target via the GABA(A) Receptor.Increased behavioral responses to ethanol in Lmo3 knockout mice Binge alcohol drinking elicits persistent negative affect in mice.TLR4-MyD88 signalling: a molecular target for alcohol actions Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice The genetics of addiction-a translational perspective Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration Neuroimmune mechanisms in fetal alcohol spectrum disorder Amitifadine, a triple monoamine uptake inhibitor, reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology.Neuroimmune mechanisms of alcohol and drug addiction.Risky Business: Pathways to Progress in Biologically Informed Studies of Psychopathology.Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRF Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABA(A) mechanism Efficient subtractive cloning of genes activated by lipopolysaccharide and interferon γ in primary-cultured cortical cells of newborn mice TLR4 signaling in VTA dopaminergic neurons regulates impulsivity through tyrosine hydroxylase modulation.Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice.Bioinformatics analyses reveal age-specific neuroimmune modulation as a target for treatment of high ethanol drinking.

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P2860

Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala

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2011 nî lūn-bûn

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Werner Sieghart

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P2860

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.

Nucleus accumbens adenosine A2A receptors regulate exertion of effort by acting on the ventral striatopallidal pathway

Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents.

Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila.

Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors.

Dimensional anxiety mediates linkage of GABRA2 haplotypes with alcoholism.

Health care access among U.S. adults who drink alcohol excessively: missed opportunities for prevention.

Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations.

gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions.

Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior.

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