Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II
about
Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy studyEnzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesisPolymorphisms in the xylosyltransferase genes cause higher serum XT-I activity in patients with pseudoxanthoma elasticum (PXE) and are involved in a severe disease courseHomozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defectsHuman xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activityHuman xylosyltransferase I and N-terminal truncated forms: functional characterization of the core enzymeEnzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivoXT-II, the second isoform of human peptide-O-xylosyltransferase, displays enzymatic activityHuman genetic disorders and knockout mice deficient in glycosaminoglycanAnalysis of the DXD motifs in human xylosyltransferase I required for enzyme activitySkeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesisThe terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation.Functional characterization of Drosophila melanogaster peptide O-xylosyltransferase, the key enzyme for proteoglycan chain initiation and member of the core 2/I N-acetylglucosaminyltransferase family.Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblasts.Initiation of the decorin glycosaminoglycan chain in the endoplasmic reticulum-Golgi intermediate compartment.Determination of the glycosaminoglycan-protein linkage region oligosaccharide structures of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans.Inhibition of heparan sulfate and chondroitin sulfate proteoglycan biosynthesisThe effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma.Biosynthesis of a new UDP-sugar, UDP-2-acetamido-2-deoxyxylose, in the human pathogen Bacillus cereus subspecies cytotoxis NVH 391-98.Systemic inflammatory response to smoking in chronic obstructive pulmonary disease: evidence of a gender effect.Identification of a bifunctional UDP-4-keto-pentose/UDP-xylose synthase in the plant pathogenic bacterium Ralstonia solanacearum strain GMI1000, a distinct member of the 4,6-dehydratase and decarboxylase family.Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders.Defective initiation of glycosaminoglycan synthesis due to B3GALT6 mutations causes a pleiotropic Ehlers-Danlos-syndrome-like connective tissue disorder.Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds.Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine.Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities.The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif.Chondroitin sulfate synthase-3. Molecular cloning and characterization.Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-proCloning and recombinant expression of active full-length xylosyltransferase I (XT-I) and characterization of subcellular localization of XT-I and XT-II.Biosynthesis of chondroitin and heparan sulfate in chinese hamster ovary cells depends on xylosyltransferase II.Transforming growth factor beta1-regulated xylosyltransferase I activity in human cardiac fibroblasts and its impact for myocardial remodeling.First description of the complete human xylosyltransferase-I promoter regionTissue engineering: chondrocytes and cartilageBiosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase.Functional UDP-xylose transport across the endoplasmic reticulum/Golgi membrane in a Chinese hamster ovary cell mutant defective in UDP-xylose SynthaseSmad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycansThe glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans.Efficient and stereocontrolled synthesis of chondroitin mono- and disaccharide linked to variously sulfated biotinylated trisaccharides of the linkage region of proteoglycans.
P2860
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P2860
Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Molecular cloning and expressi ...... se and its first isoform XT-II
@ast
Molecular cloning and expressi ...... se and its first isoform XT-II
@en
Molecular cloning and expressi ...... se and its first isoform XT-II
@en-gb
Molecular cloning and expressi ...... se and its first isoform XT-II
@nl
type
label
Molecular cloning and expressi ...... se and its first isoform XT-II
@ast
Molecular cloning and expressi ...... se and its first isoform XT-II
@en
Molecular cloning and expressi ...... se and its first isoform XT-II
@en-gb
Molecular cloning and expressi ...... se and its first isoform XT-II
@nl
prefLabel
Molecular cloning and expressi ...... se and its first isoform XT-II
@ast
Molecular cloning and expressi ...... se and its first isoform XT-II
@en
Molecular cloning and expressi ...... se and its first isoform XT-II
@en-gb
Molecular cloning and expressi ...... se and its first isoform XT-II
@nl
P2093
P921
P356
P1476
Molecular cloning and expressi ...... se and its first isoform XT-II
@en
P2093
P304
P356
10.1006/JMBI.2000.4261
P407
P577
2000-12-08T00:00:00Z