Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
about
The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overloadDisruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathyExome sequencing identifies a mutation in the ACTN2 gene in a family with idiopathic ventricular fibrillation, left ventricular noncompaction, and sudden deathNebulin regulates thin filament length, contractility, and Z-disk structure in vivo.Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosisCooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscleInteraction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulinANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 siteMutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathyPalladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodelingSorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophyNebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscleStructure and function of palladin's actin binding domain.Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodelingZyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1Myotilin dynamics in cardiac and skeletal muscle cellsTargeting the sarcomere to correct muscle functionMolecular analysis of the interaction between palladin and alpha-actininA class III PDZ binding motif in the myotilin and FATZ families binds enigma family proteins: a common link for Z-disc myopathiesAnalysis of myotilin turnover provides mechanistic insight into the role of myotilinopathy-causing mutationsStructural and regulatory roles of muscle ankyrin repeat protein family in skeletal muscleArpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervationBiallelic Mutations in MYPN, Encoding Myopalladin, Are Associated with Childhood-Onset, Slowly Progressive Nemaline MyopathyThe nebulin SH3 domain is dispensable for normal skeletal muscle structure but is required for effective active load bearing in mouse.Congenital myopathies: diseases of the actin cytoskeleton.The actin associated protein palladin in smooth muscle and in the development of diseases of the cardiovasculature and in cancer.Micromechanical regulation in cardiac myocytes and fibroblasts: implications for tissue remodelingMyogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.Nebulin plays a direct role in promoting strong actin-myosin interactions.Dissection of Z-disc myopalladin gene network involved in the development of restrictive cardiomyopathy using system genetics approachCharacterization of cytoskeleton features and maturation status of cultured human iPSC-derived cardiomyocytes.Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction.Nebulin regulates actin filament lengths by a stabilization mechanism.Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulationMechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?Carp, a cardiac ankyrin-repeated protein, and its new homologue, Arpp, are differentially expressed in heart, skeletal muscle, and rhabdomyosarcomasDynamic regulation of sarcomeric actin filaments in striated muscleMolecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutationsGenomic variation in seven Khoe-San groups reveals adaptation and complex African history.
P2860
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P248
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P2860
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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name
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@ast
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en-gb
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@nl
type
label
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@ast
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en-gb
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@nl
prefLabel
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@ast
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en-gb
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@nl
P2093
P2860
P921
P3181
P356
P1476
Myopalladin, a novel 145-kilod ...... and I-band protein assemblies
@en
P2093
A S McElhinny
C C Gregorio
H Granzier
H Sorimachi
K Trombitás
R Yamasaki
P2860
P304
P3181
P356
10.1083/JCB.153.2.413
P407
P577
2001-04-16T00:00:00Z