E2F transcriptional activation requires TRRAP and GCN5 cofactors
about
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformationThe adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complexAnd-1 is required for the stability of histone acetyltransferase Gcn5The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repairTranscriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexesTRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins.E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferasesSGF29 and Sry pathway in hepatocarcinogenesisc-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activationTIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosisConstruction and clarification of dynamic gene regulatory network of cancer cell cycle via microarray data.A human functional protein interaction network and its application to cancer data analysisE mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif.Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans.Gcn5 and PCAF regulate PPARĪ³ and Prdm16 expression to facilitate brown adipogenesisSp1 facilitates DNA double-strand break repair through a nontranscriptional mechanismHistone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics.GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage.Orchestration of chromatin-based processes: mind the TRRAP.Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity.Emerging roles of E2Fs in cancer: an exit from cell cycle controlPrenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice.Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytesE2F inhibition synergizes with paclitaxel in lung cancer cell linesTudor staphylococcal nuclease (Tudor-SN), a novel regulator facilitating G1/S phase transition, acting as a co-activator of E2F-1 in cell cycle regulation.E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.High throughput screening identifies modulators of histone deacetylase inhibitorsThe stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferationTranscriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation.Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.RB1, development, and cancer.Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expressionHistone acetyltransferase inhibitors and preclinical studies.Novel functions for the transcription factor E2F4 in development and disease.E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.Role of host cell factor-1 in cell cycle regulation.Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy?
P2860
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P248
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P2860
E2F transcriptional activation requires TRRAP and GCN5 cofactors
description
2001 nĆ® lÅ«n-bĆ»n
@nan
2001 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2001 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Ö
Õ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2001幓ć®č«ę
@ja
2001幓å¦ęÆęē«
@wuu
2001幓å¦ęÆęē«
@zh-cn
2001幓å¦ęÆęē«
@zh-hans
2001幓å¦ęÆęē«
@zh-my
2001幓å¦ęÆęē«
@zh-sg
2001幓åøč”ęē«
@yue
name
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@ast
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en-gb
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@nl
type
label
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@ast
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en-gb
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@nl
prefLabel
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@ast
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en-gb
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@nl
P2093
P2860
P921
P3181
P356
P1476
E2F transcriptional activation requires TRRAP and GCN5 cofactors
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M102067200
P407
P577
2001-08-31T00:00:00Z