Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF - Test2 - elhamkhani - TriplyDB

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

http://www.wikidata.org/entity/Q24291941

about

Nonhuman genetics. Genomic basis for the convergent evolution of electric organs Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway Critical role for Kalirin in nerve growth factor signaling through TrkA.The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction.The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.Direct interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factor B plexins activate Rho through PDZ-RhoGEF Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules Biochemical and computational analysis of LNX1 interacting proteins LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.Non-canonical functions of RGS proteins Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF Aging and gastrointestinal neuromuscular function: insights from within and outside the gut.Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13 Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis.Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation Unc5B associates with LARG to mediate the action of repulsive guidance molecule.A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.Regulation and physiological functions of G12/13-mediated signaling pathways.Regulation of RhoGEF proteins by G12/13-coupled receptors.Cadherin-mediated intercellular adhesion and signaling cascades involving small GTPases.PDZ domains: the building blocks regulating tumorigenesis.G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery.Chimeric G alpha i2/G alpha 13 proteins reveal the structural requirements for the binding and activation of the RGS-like (RGL)-containing Rho guanine nucleotide exchange factors (GEFs) by G alpha 13.Potentiation of hematopoietic cell migration with an IGF-interleukin-3 fusion protein.The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori.

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P2860

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

http://www.wikidata.org/entity/Q24291941

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2001 nî lūn-bûn

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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2001年の論文

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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Journal of Cell Biology

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Direct interaction of insulin- ...... ith leukemia-associated RhoGEF

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A Iwamatsu

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H Makino

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H Sengiku

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I Urakawa

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K Nagao

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N Inagaki

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S Kataoka

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S Taya

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P2860

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Rho GTPases and the actin cytoskeleton

Mammalian Ras interacts directly with the serine/threonine kinase Raf

Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase

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809-20

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10.1083/JCB.200106139

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