SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) - Test2 - elhamkhani - TriplyDB

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

http://www.wikidata.org/entity/Q24292189

about

Research progress on Livin protein: an inhibitor of apoptosis Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway SMAC is expressed de novo in a subset of cervical cancer tumors Targeting Cell Survival Proteins for Cancer Cell Death Targeting the apoptosis pathway in hematologic malignancies Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis Expression of BIRC7 protein and mRNA in non-Hodgkin's lymphoma The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9 Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.High Smac/DIABLO expression is associated with early local recurrence of cervical cancer A specificity map for the PDZ domain family Immunity to the melanoma inhibitor of apoptosis protein (ML-IAP; livin) in patients with malignant melanoma.XIAP impairs Smac release from the mitochondria during apoptosis.Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas The protein structures that shape caspase activity, specificity, activation and inhibition.Inhibitor of apoptosis proteins: new therapeutic targets in hematological cancer?USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration Recent advances in the use of protein transduction domains for the delivery of peptides, proteins and nucleic acids in vivo.Apoptosis is induced in cancer cells via the mitochondrial pathway by the novel xylocydine-derived compound JRS-15.A gene to organism approach--assessing the impact of environmental pollution in eelpout (Zoarces viviparus) females and larvae.Telmisartan exerts pleiotropic effects in endothelial cells and promotes endothelial cell quiescence and survival.IAP-targeted therapies for cancer.Inhibitor of apoptosis proteins in hematological malignancies.Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways.Cell-penetrating peptides: achievements and challenges in application for cancer treatment.Small-molecule pan-IAP antagonists: a patent review.Targeting inhibitor of apoptosis proteins for therapeutic intervention.Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.Exploiting inhibitor of apoptosis proteins as therapeutic targets in hematological malignancies.Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities.Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis.Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis.Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage.Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack.c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment Synthetic Smac peptide enhances chemo-sensitivity of bladder cancer cells.Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

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P2860

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

http://www.wikidata.org/entity/Q24292189

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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P1433

Journal of Biological Chemistry

P1476

SMAC negatively regulates the ...... nhibitor of apoptosis (ML-IAP)

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P2093

Domagoj Vucic

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Heidi Ackerly

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Kurt Deshayes

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Maria Teresa Pisabarro

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Saloumeh Kadkhodayan

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Vishva M Dixit

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Wayne J Fairbrother

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

X-linked IAP is a direct inhibitor of cell-death proteases

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

P304

12275-9

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10.1074/JBC.M112045200

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P407

P433

14

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277

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2002-04-05T00:00:00Z

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11801603

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P921

apoptotic process

Baculoviral IAP repeat containing 7