Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site
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Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selectionIncreasing the Conformational Entropy of the Ω-Loop Lid Domain in Phosphoenolpyruvate Carboxykinase Impairs Catalysis and Decreases Catalytic Fidelity,The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?Structural and functional studies of phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosisPhosphoenolpyruvate carboxykinase 1 gene (Pck1) displays parallel evolution between Old World and New World fruit batsA putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis.The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria.Structural insights into the mechanism of phosphoenolpyruvate carboxykinase catalysis.Nucleotide selectivity of antibiotic kinases.First characterization of an archaeal GTP-dependent phosphoenolpyruvate carboxykinase from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1.Phylogenetic study of the evolution of PEP-carboxykinase.Thematic minireview series: a perspective on the biology of phosphoenolpyruvate carboxykinase 55 years after its discovery.Dynamic behavior of rat phosphoenolpyruvate carboxykinase inhibitors: new mechanism for enzyme inhibition.Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenolpyruvate carboxykinase determined by fluorescence spectroscopy.The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.Roles of Asp75, Asp78, and Glu83 of GTP-dependent phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis.Tyr235 of human cytosolic phosphoenolpyruvate carboxykinase influences catalysis through an anion-quadrupole interaction with phosphoenolpyruvate carboxylate.Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma.oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2A computational study on role of 6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxyoxane-2,4,5-triol in the regulation of blood glucose level.In SilicoCharacterization and Homology Modeling of a Cyanobacterial Phosphoenolpyruvate Carboxykinase Enzyme
P2860
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P2860
Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
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2002年论文
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name
Crystal structure of human cyt ...... reveals a new GTP-binding site
@ast
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en-gb
Crystal structure of human cyt ...... reveals a new GTP-binding site
@nl
type
label
Crystal structure of human cyt ...... reveals a new GTP-binding site
@ast
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en-gb
Crystal structure of human cyt ...... reveals a new GTP-binding site
@nl
prefLabel
Crystal structure of human cyt ...... reveals a new GTP-binding site
@ast
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en-gb
Crystal structure of human cyt ...... reveals a new GTP-binding site
@nl
P2093
P921
P356
P1476
Crystal structure of human cyt ...... reveals a new GTP-binding site
@en
P2093
Charles Belunis
David Weber
Gwendolyn B Ramsey
Hanspeter Michel
Kurt Hollfelder
Pete Dunten
Robert Crowther
Stanley J Wertheimer
Ursula Kammlott
P304
P356
10.1006/JMBI.2001.5364
P407
P577
2002-02-15T00:00:00Z