Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
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Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoterE2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 proteinThe AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLFSite-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemiaFusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemiaPivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytesThe rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferencesDNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLFDNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion proteinAnalysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targetingVBP and RelA regulate avian leukosis virus long terminal repeat-enhanced transcription in B cellsControl of apoptosis by asymmetric cell divisionCharacterization of the mUBC9-binding sites required for E2A protein degradationCloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemiaGATA factors are essential for transcription of the survival gene E4bp4 and the viability response of interleukin-3 in Ba/F3 hematopoietic cellsIdentification of multiple transcription factors, HLF, FTF, and E4BP4, controlling hepatitis B virus enhancer II.B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partnersCandidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes.Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo.The C/EBP family of transcription factors in the liver and other organs.Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic miceD-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300.The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior.Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes.Role for homodimerization in growth deregulation by E2a fusion proteins.CREB is one component of the binding complex of the Ces-2/E2A-HLF binding element and is an integral part of the interleukin-3 survival signal.De novo transcriptome sequencing analysis and comparison of differentially expressed genes (DEGs) in Macrobrachium rosenbergii in China.E2A-HLF usurps control of evolutionarily conserved survival pathways.The loss of circadian PAR bZip transcription factors results in epilepsy.Gene expression profiling combined with bioinformatics analysis identify biomarkers for Parkinson disease.CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP.MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia.Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia.Conditional Expression of E2A-HLF Induces B-Cell Precursor Death and Myeloproliferative-Like Disease in Knock-In Mice.MicroRNA-21 regulates prostaglandin E2 signaling pathway by targeting 15-hydroxyprostaglandin dehydrogenase in tongue squamous cell carcinomaMolecular genetics of B-precursor acute lymphoblastic leukemiaStructure and expression of the human trithorax-like gene 1 involved in acute leukemias.DNA-binding specificity of the PAR basic leucine zipper protein VBP partially overlaps those of the C/EBP and CREB/ATF families and is influenced by domains that flank the core basic region
P2860
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P2860
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@ast
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en-gb
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@nl
type
label
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@ast
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en-gb
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@nl
prefLabel
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@ast
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en-gb
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@nl
P2093
P921
P3181
P356
P1433
P1476
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
@en
P2093
L H Shapiro
S C Raimondi
W M Roberts
P3181
P356
10.1126/SCIENCE.1386162
P407
P577
1992-07-24T00:00:00Z