ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
about
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epitheliumGenetic variants associated with breast size also influence breast cancer riskLuminal breast cancer cell lines overexpressing ZNF703 are resistant to tamoxifen through activation of Akt/mTOR signalingEvolution of the NET (NocA, Nlz, Elbow, TLP-1) protein family in metazoans: insights from expression data and phylogenetic analysis.ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3).Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omicsThe Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion.Lobular breast cancer: molecular basis, mouse and cellular models.Genetic dissection of photoreceptor subtype specification by the Drosophila melanogaster zinc finger proteins elbow and no ocelli.The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression.Cyclin alterations in diverse cancers: Outcome and co-amplification network.Who is in the driver's seat in 8p12 amplifications? ZNF703 in luminal B breast tumors.Elevated ZNF703 Protein Expression Is an Independent Unfavorable Prognostic Factor for Survival of the Patients with Head and Neck Squamous Cell CarcinomaEngineering targeted chromosomal amplifications in human breast epithelial cellsLuminal-B breast cancer and novel therapeutic targets.Basal breast cancer: a complex and deadly molecular subtypeDivide and conquer: the genetic basis of molecular subclassification of breast cancer.Extensive Transcriptomic and Genomic Analysis Provides New Insights about Luminal Breast Cancers.Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer.Functional characterization of the 19q12 amplicon in grade III breast cancersnlz1 is required for cilia formation in zebrafish embryogenesis.A new genome-driven integrated classification of breast cancer and its implications.A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression.Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse.Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex.Integrated genomic analysis of breast cancers.High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancerEndoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cellsCo-transcriptional R-loops are the main cause of estrogen-induced DNA damage.ZNF703 Overexpression may act as an oncogene in non-small cell lung cancer.Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profilingEstrogen receptor-positive breast cancer molecular signatures and therapeutic potentials (Review).An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer.Overexpression of ZNF703 facilitates tumorigenesis and predicts unfavorable prognosis in patients with cholangiocarcinoma.The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.Whole exome sequencing of a patient with metastatic hidradenocarcinoma and review of the literature.ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression.Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas.Amplification of chromosome 8 genes in lung cancer.
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P2860
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@ast
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en-gb
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@nl
type
label
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@ast
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en-gb
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@nl
prefLabel
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@ast
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en-gb
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@nl
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P2860
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P1476
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
@en
P2093
Anthony Ferrari
Aurélie Lonigro
Christophe Ginestier
Christos Sotiriou
Cornel Popovici
Daniel Birnbaum
Emilie Baudelet
Estelle Rousselet
Fabrice Sircoulomb
François Bertucci
P2860
P304
P3181
P356
10.1002/EMMM.201100121
P407
P577
2011-03-01T00:00:00Z