Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O
about
High incidence of somatic BAP1 alterations in sporadic malignant mesotheliomaE2 enzymes: more than just middle menThe business of deubiquitination - location, location, locationDeubiquitinating enzymes in cellular signaling and disease regulationLoss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors.Consensus report of the 2015 Weinman International Conference on MesotheliomaThe LMO2 oncogene regulates DNA replication in hematopoietic cellsCytoplasmic expression of BAP1 as an independent prognostic biomarker for patients with gliomasRecent insights emerging from malignant mesothelioma genome sequencingBAP1 hereditary cancer predisposition syndrome: a case report and review of literaturePositive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesotheliomaNipah virus matrix protein: expert hacker of cellular machines.Molecular architecture of polycomb repressive complexesDeubiquitylation of deubiquitylasesThe ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosisThe BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteinsBAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5.Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma.Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity.Mechanisms of regulation and diversification of deubiquitylating enzyme function.BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.BAP1/ASXL1 recruitment and activation for H2A deubiquitination.Cancer associated missense mutations in BAP1 catalytic domain induce amyloidogenic aggregation: A new insight in enzymatic inactivation.Gene of the month: BAP1.Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cellsBAP1 mutations in high-grade meningioma: implications for patient care.PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.UBE2O is a quality control factor for orphans of multiprotein complexes.UBE2O remodels the proteome during terminal erythroid differentiation.Tissue-specific significance of BAP1 gene mutation in prognostic prediction and molecular taxonomy among different types of cancer.Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma.Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.A new duet in cancer biology: AMPK the typical and UBE2O the atypical.A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.New Insights into the Role of E2s in the Pathogenesis of Diseases: Lessons Learned from UBE2O.The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.Topologically knotted deubiquitinases exhibit unprecedented mechanostability to withstand the proteolysis by an AAA+ protease.Detecting germline BAP1 mutations in patients with peritoneal mesothelioma: benefits to patient and family members.Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1
P2860
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P2860
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@ast
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en-gb
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@nl
type
label
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@ast
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en-gb
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@nl
prefLabel
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@ast
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en-gb
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@nl
P2093
P921
P3181
P1433
P1476
Autodeubiquitination protects ...... typical ubiquitin ligase UBE2O
@en
P2093
El Bachir Affar
Haider H Dar
Haithem Barbour
Ian Hammond-Martel
Jessica Gagnon
Marc Therrien
Nadine N Sen
Nazar Mashtalir
Salima Daou
P304
P3181
P356
10.1016/J.MOLCEL.2014.03.002
P407
P577
2014-05-08T00:00:00Z