The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
about
Chromatin perturbations during the DNA damage response in higher eukaryotesB cells in chronic graft-versus-host diseaseMechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer CellsAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerThe Role of the DNA Damage Response throughout the Papillomavirus Life CycleBrd4 activates P-TEFb for RNA polymerase II CTD phosphorylationThe mechanisms behind the therapeutic activity of BET bromodomain inhibitionTargeting BET bromodomains for cancer treatmentDrosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levelsKeap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain ProteinDrug Discovery Targeting Bromodomain-Containing Protein 4.Characterization of BRD4 during mammalian postmeiotic sperm development.A Multivariate Computational Method to Analyze High-Content RNAi Screening DataHiFive: a tool suite for easy and efficient HiC and 5C data analysisPapillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target.Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice.BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphomaBRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.Molecular mechanisms of retroviral integration site selection.Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4.Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probesInducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibitionThe condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores.Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.BRD4 inhibitor inhibits colorectal cancer growth and metastasis.Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cellsBrd4 is displaced from HPV replication factories as they expand and amplify viral DNAStress-induced nuclear RNA degradation pathways regulate yeast bromodomain factor 2 to promote cell survival.A Novobiocin Derivative, XN4, Inhibits the Proliferation of Chronic Myeloid Leukemia Cells by Inducing Oxidative DNA DamageBromodomain inhibitors regulate the C9ORF72 locus in ALSShelterin Protects Chromosome Ends by Compacting Telomeric ChromatinMapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.The converging roles of BRD4 and gene transcription in pluripotency and oncogenesisRNAi screens identify CHD4 as an essential gene in breast cancer growth.Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AXBRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.
P2860
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P2860
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@ast
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en-gb
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@nl
type
label
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@ast
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en-gb
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@nl
prefLabel
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@ast
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en-gb
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
@en
P2093
Amanda M Del Rosario
Amanda Maffa
Anna Fydrych
Anne E Carpenter
Benjamin A Greenberger
Bryan D Bryson
Clark C Chen
David E Root
Emily J Blake
Fred C Lam
P2860
P2888
P304
P3181
P356
10.1038/NATURE12147
P407
P577
2013-06-02T00:00:00Z
P5875
P6179
1016822016