HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines
about
Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replicationFuture classes of hepatitis C virus therapeutic agentsDirect acting antivirals for the treatment of chronic viral hepatitisInnate immune responses in hepatitis C virus infectionClassical swine fever virus NS5A protein changed inflammatory cytokine secretion in porcine alveolar macrophages by inhibiting the NF-κB signaling pathwayThe N-terminal region of severe acute respiratory syndrome coronavirus protein 6 induces membrane rearrangement and enhances virus replication.PCBP2 enhances the antiviral activity of IFN-α against HCV by stabilizing the mRNA of STAT1 and STAT2.Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytesHepatitis C virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-alpha through dephosphorylation.Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells.Transcriptional repression of C4 complement by hepatitis C virus proteins.Intrinsic Viral Factors Are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice.Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver.Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells.Impact of host and virus genome variability on HCV replication and response to interferon.Hepatitis C virus (HCV) employs multiple strategies to subvert the host innate antiviral response.The role of HCV proteins on treatment outcomes.Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18.Tricistronic hepatitis C virus subgenomic replicon expressing double transgenes.Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cells.TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION.Increased incidence of cytomegalovirus coinfection in HCV-infected patients with late liver fibrosis is associated with dysregulation of JAK-STAT pathway.HCV NS5A and IRF9 compete for CypA binding.Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling.Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling.
P2860
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P2860
HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@ast
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en-gb
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@nl
type
label
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@ast
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en-gb
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@nl
prefLabel
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@ast
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en-gb
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@nl
P2093
P921
P3181
P1476
HCV NS5A inhibits interferon-a ...... hepatocyte-derived cell lines
@en
P2093
Full-Young Chang
Keng-Hsin Lan
Keng-Li Lan
Meei-Ling Sheu
Ming-Yuan Chen
Sang-Hue Yen
Shou-Dong Lee
Wei-Ping Lee
Yung-Lu Lee
P304
P3181
P356
10.1016/J.JHEP.2006.11.013
P407
P577
2007-05-01T00:00:00Z