Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
about
Transcription factor Zic2 inhibits Wnt/β-catenin protein signalingTrial watch - inhibiting PARP enzymes for anticancer therapyPoly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and TumorogenesisColorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in cultureKu proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines.Emergence of TNIK inhibitors in cancer therapeutics.Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAMTraf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and β-catenin accumulationBiological and clinical significance of PARP1 protein expression in breast cancer.CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.PolyADP-ribosylation and cancer.Ku70 functions in addition to nonhomologous end joining in pancreatic β-cells: a connection to β-catenin regulationWnt signaling inside the nucleus.Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesisHepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.β-Catenin induces T-cell transformation by promoting genomic instability.From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.Transcriptional roles of PARP1 in cancer.Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis.The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1.UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy.High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.Activation of PARP-1 in response to bleomycin depends on the Ku antigen and protein phosphatase 5.PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells.Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin.PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic C. Elegans And Improves GLP-1 Secretion in Human Cells.Overexpression of IRS-4 Correlates with Procaspase 3 Levels in Tumoural Tissue of Patients with Colorectal Cancer
P2860
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P2860
Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@ast
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en-gb
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@nl
type
label
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@ast
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en-gb
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@nl
prefLabel
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@ast
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en-gb
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@nl
P2093
P3181
P1433
P1476
Ku70 and poly(ADP-ribose) poly ...... recognition and Wnt signaling
@en
P2093
Kazufumi Honda
Kohzoh Imai
Masashi Idogawa
Miki Shitashige
Mitsuko Masutani
Setsuo Hirohashi
Takashi Tokino
Tesshi Yamada
Yasuhisa Shinomura
P3181
P356
10.1158/0008-5472.CAN-06-2360
P407
P577
2007-02-01T00:00:00Z