An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium - Test2 - elhamkhani - TriplyDB

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

http://www.wikidata.org/entity/Q24297497

about

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo Ciliary Extracellular Vesicles: Txt Msg Organelles Molecular views of Arf-like small GTPases in cilia and ciliopathies Molecular complexes that direct rhodopsin transport to primary cilia Ciliary subcompartments: how are they established and what are their functions?Compartments within a compartment: what C. elegans can tell us about ciliary subdomain composition, biogenesis, function, and disease PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity Daughter cell identity emerges from the interplay of Cdc42, septins, and exocytosis The emerging role of Arf/Arl small GTPases in cilia and ciliopathies.ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting Trafficking in and to the primary cilium.The roles of evolutionarily conserved functional modules in cilia-related trafficking.IFT-Cargo Interactions and Protein Transport in Cilia Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice Ablation of the X-linked retinitis pigmentosa 2 (Rp2) gene in mice results in opsin mislocalization and photoreceptor degeneration Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis Membrane protein transport in photoreceptors: the function of PDEδ: the Proctor lecture Trafficking to the primary cilium membrane.From the cytoplasm into the cilium: bon voyage.Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d (- /-) cones.Ciliopathies: the trafficking connection.Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism The nphp-2 and arl-13 genetic modules interact to regulate ciliogenesis and ciliary microtubule patterning in C. elegans.The solution structure of the transducin-α-uncoordinated 119 protein complex suggests occlusion of the Gβ₁γ₁-binding sites.Mistrafficking of prenylated proteins causes retinitis pigmentosa 2.De Novo Occurrence of a Variant in ARL3 and Apparent Autosomal Dominant Transmission of Retinitis Pigmentosa Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access.Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis Senior-Løken syndrome: a syndromic form of retinal dystrophy associated with nephronophthisis.Expression and subcellular distribution of UNC119a, a protein partner of transducin α subunit in rod photoreceptors.Uncoordinated (UNC)119: coordinating the trafficking of myristoylated proteins.A paneukaryotic genomic analysis of the small GTPase RABL2 underscores the significance of recurrent gene loss in eukaryote evolution.Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa

P2860

15af1bbf2f8346ab0947033966d027e0caa4b66b 2284aecd7c3e00dd4649cf197c4b8868f641cb98 27a64c4c96ce56904f59d9f73bf0a8826c5eee7b 2c80db14223fa2e4624254368486cf6e19d83637 2ee1b5e994b9ccba766368c2791e22f0ecdcebdd 38742f987248943bb3566cf277b5e5b660d7d8e9 49773c6b696ef99ef2c44724bf4991f5913cade7 5b051e39e8c525473b511c55dd07584b5b288aa3 5dc0c44e70ef85f49d62ee64ede3818428fa752e 6d80e1d2dc1574d32c79cc34e1f5eef7efea32ff 73776509c18e462a0bec3f2f46bb78cf5dec4a08 7c0eb662a037dfa412810fbb2b6b8f3ef77dbad4 94a68cd4d73b84ab604a7cc9fb2a9afe25f5eadc 988ce12c0bbe4ccf5b2484795564ad063bb33ff0 a9e60c6287cdd71cdcbc93fd3f2b4438707b716f b629d99558627bbc892e929d303b1f0cc590ca97 bee2bd52624864c44d017a257ff996abb94178b1 c1ffcb8cf23dd748bcdffd4655f709eea9fd73e6 c25f0413b3adcb1c1a18b67afbe55203c85d2ace c30c492846af2da6f75ee43b436f0893bd1c3923 c51f173b3a193af5ab6484f4abe19002b49f4768 e94323d9ff4b28500eff5950ea77e21fb2488a78 f7b77d7830abebea95e05719bec015f6bf0fb4bf fe9de5f6e171f686571aff454877fc1dc154f03f

P248

Q24293500-8780E854-112B-4074-BE59-99F744A3430E Q24298355-74D2AF6B-1B19-4C55-A938-3B773DAA8CC1 Q24319185-4AEDE538-34F2-4AE8-A498-EB2102F10B93 Q24337437-711B88E2-408C-43A2-80A3-D22A61715448 Q24337852-A165E73D-FFC0-4F2A-83E0-2CE9A9C36EC2 Q26764992-F233075C-A3EE-460F-9988-A1319A529CFD Q26830180-F34A7D04-36AE-4A07-8DC4-2D631B074E79 Q26860718-B9E80318-54EF-4259-A8A5-6A99AC370CEE Q26999913-F01E39C3-D652-45CF-B61B-429DBD680181 Q27025518-6D42B20C-A454-4E9E-B573-C699A7EB789B Q27704536-3D1B913E-D26D-4C17-9671-32FB76119A6D Q27934066-BD38E42A-CD6A-4471-9123-AD5FC46797A0 Q28000091-F2454A95-FBC4-4704-898C-F8EC4D805E4C Q28000117-95E89CA2-D981-47B7-8740-F3ECA9BF5D31 Q28000124-ACBC0BC1-B761-4D17-ADBF-FC8088293C18 Q28000150-DDE2ED81-143E-4F6E-AC55-DD4877ECA6EF Q28085246-CCB80FA2-E525-40D7-B412-A4F7EE659A28 Q28267539-FC3E5A60-EA32-496D-95DA-B71748BE45E0 Q28292199-7EC80EC2-9B68-40BB-9D7D-DED6827A9B12 Q28312140-4027FCAB-6FD6-4135-8BF8-D422A67DC0B8 Q28590707-2CDF53C6-820D-43A9-811A-7671F8967AC8 Q28610521-4D049D08-9E15-483B-AA25-AE36564F7A7B Q30353488-0B95E517-ACBE-4FEC-8A7F-4CB5751C462C Q33728229-49E70A02-DA61-46DF-B031-B5D4C9150D06 Q33844328-60FE3AE5-BA41-4BBB-BC7C-F6457D3BDBE0 Q34207085-DA818E7B-7CD6-48E7-BD50-2F620F378757 Q34442266-084DD164-1EEA-40AE-8589-EB9D5518F0D9 Q34541792-5E9913BF-33EB-4985-AEC3-4A0645061CCF Q34679993-7C0856FF-2826-41B5-A28F-D3BAA5D690E0 Q35028004-04312B05-CBAB-403F-9382-527D91A5F2DA Q35576525-5E79BF65-CB2C-4715-8D25-C95CC4159BD1 Q35952846-0DA5BC82-A2F5-4A0B-AE61-A265F5652B4A Q36027360-BF63D7E3-5DE6-46EA-9E43-D7FEEBA4EB7B Q36063776-F07AAF35-E074-4D16-AB86-B5E345F4F401 Q36417359-8A6D0D54-5637-416F-B0F0-BA2CEED1FA19 Q36428182-55A82C9E-5581-4C47-A296-5CD4F681451F Q36446252-444A8FC0-852D-42B7-8A5F-5B0344FCE491 Q36529854-1680A4DC-93D4-4FC3-A03D-99481A1919A7 Q36727473-FAA98763-9517-427F-90FD-74C20A67FCC2 Q37083413-4B0F5C19-7FEC-4369-9AC1-9241AF462473

P2860

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

http://www.wikidata.org/entity/Q24297497

description

2011 nî lūn-bûn

@nan

2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@ast

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en-gb

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@nl

type

label

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@ast

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en-gb

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@nl

prefLabel

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@ast

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@en-gb

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

@nl

P1433

Q24297497-AD341727-4C9C-4526-940E-F003197C727D

P1476

Q24297497-59B18DE9-ACC2-4D72-BA8E-31EC7113B69D

P2093

Q24297497-1BB27168-24EC-40AD-82EF-933D85A9829F

Q24297497-4EF2B108-9E6F-492D-BD5F-69F64E1FAB98

Q24297497-74AF97D1-CA32-401F-BAE7-743FBC4F36B6

Q24297497-86A85E30-A7DE-4837-B176-80A390176A2E

Q24297497-8824005B-DD1D-472C-8F0B-FE3D3D3E25B6

Q24297497-8DB0DE45-7D51-493B-B6F6-29D5B24E2CFD

Q24297497-99F072D0-1072-4B79-9ACF-995BA4A09DFA

Q24297497-9A62282D-53AC-4F1F-9222-5F4A11396812

Q24297497-A67C6533-B9DA-4E2D-89C1-431121B0D713

Q24297497-CA28E3D8-51BE-4F05-A248-E03A1529AFCD

P2860

Q24297497-0BBD1013-D923-4F84-B4AA-779DEE626B80

Q24297497-0F3F62C0-B201-4D19-987D-A34FE68DBC27

Q24297497-113A23D3-3007-497B-A766-C9F954C491B2

Q24297497-183837F2-8A41-4285-A921-D3C6D5B8BACA

Q24297497-1CEFDD08-5C9A-4E8C-8A72-4891FC3C5D71

Q24297497-31898D42-DE84-48D2-8B1E-765257D46DE3

Q24297497-3482358E-2EE5-41B2-9497-A6A7055DCE41

Q24297497-38833B25-23B7-46A4-BC58-E457A8BF15A4

Q24297497-3B01F507-8405-472E-BDED-FFFEE4B93A33

Q24297497-53CD0A15-B214-4CF0-ADE6-EB329366BACB

P304

Q24297497-37C6A123-A852-4B8A-A90C-A9490966DA96

P31

Q24297497-94F6A2BB-21D9-4579-B35F-7876BCE846F5

P3181

Q24297497-2AC3AA55-D5BC-4E79-97E1-EB780A94C577

P356

Q24297497-60A3C388-7683-4D0D-B0C9-AF012174804F

P407

Q24297497-D17585D9-704D-424C-A31F-D191E13EECD1

P433

Q24297497-BD061C57-C8C2-453D-8BB9-9FF084D61961

P478

Q24297497-8E229006-3DB2-4D13-A8AF-36F712B1E4DB

P577

Q24297497-C838DF1F-2AD9-42A7-A63B-AD3305B6F6CD

P5875

Q24297497-5DDAFCD6-0428-4918-90A9-2C70BFBFA616

P698

Q24297497-90AF1BE4-A54E-43A3-A206-392735A43B69

P921

Q24297497-20577364-4648-4072-950F-2047E02DCE20

Q24297497-350047B6-CDD9-4F28-B6EA-7B9CDE1130B1

Q24297497-A075C615-CC02-4CCB-AFCB-D8417B99A568

Q24297497-A0950C5E-B3DF-45B7-81D8-28BC2594B652

Q24297497-EA0A20CF-9287-4369-B102-1D9D0D995D99

P932

Q24297497-1BE33830-C9AA-4360-B810-8916D43C0502

P3181

P356

P1433

Genes & Development

P1476

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium.

@en

P2093

Anique Olivier-Mason

http://www.w3.org/2001/XMLSchema#string

Diane C Slusarski

http://www.w3.org/2001/XMLSchema#string

Kevin J Wright

http://www.w3.org/2001/XMLSchema#string

Lisa M Baye

http://www.w3.org/2001/XMLSchema#string

Liyun Sang

http://www.w3.org/2001/XMLSchema#string

Mandy Kwong

http://www.w3.org/2001/XMLSchema#string

Pamela R Pretorius

http://www.w3.org/2001/XMLSchema#string

Peter K Jackson

http://www.w3.org/2001/XMLSchema#string

Piali Sengupta

http://www.w3.org/2001/XMLSchema#string

Saikat Mukhopadhyay

http://www.w3.org/2001/XMLSchema#string

P2860

MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins

The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization

The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium

Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

UNC119 is required for G protein trafficking in sensory neurons

Arl2 and Arl3 regulate different microtubule-dependent processes.

Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

Nephrocystin-3 is required for ciliary function in zebrafish embryos

P304

2347-60

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2150775

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.173443.111

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P577

2011-11-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51801372

http://www.w3.org/2001/XMLSchema#string

P698

22085962

http://www.w3.org/2001/XMLSchema#string

P921

ADP ribosylation factor like GTPase 3

Unc-119 lipid binding chaperone

Macrophage immunometabolism regulator

Unc-119 lipid binding chaperone B

P932

3222901

http://www.w3.org/2001/XMLSchema#string