A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
about
Origin and evolution of the peroxisomal proteome.TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulumA high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradationA membrane protein required for dislocation of misfolded proteins from the ERDefining human ERAD networks through an integrative mapping strategySEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substratesMembrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradationDerlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradationSignal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1uRegulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradationMannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation stepsThe TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ERThe UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradationUSP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradationProtein disulphide isomerase is required for signal peptide peptidase-mediated protein degradationThe otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ERRNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERADSelenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responsesRecruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membraneSVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagyCaveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complexThe tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteinsSEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosisSignal-peptide-mediated translocation is regulated by a p97-AIRAPL complexMultiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.Profile of Tom A. Rapoport.The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding siteThe retrotranslocation protein Derlin-1 binds peptide:N-glycanase to the endoplasmic reticulumEDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosolThe human selenoproteome: recent insights into functions and regulationInhibition of p97-dependent protein degradation by Eeyarestatin IOne step at a time: endoplasmic reticulum-associated degradationMurine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infectionUbiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes RiskUbiquitylation of an ERAD substrate occurs on multiple types of amino acids
P2860
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P2860
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A membrane protein complex med ...... the ER lumen into the cytosol
@ast
A membrane protein complex med ...... the ER lumen into the cytosol
@en
A membrane protein complex med ...... the ER lumen into the cytosol
@en-gb
A membrane protein complex med ...... the ER lumen into the cytosol
@nl
type
label
A membrane protein complex med ...... the ER lumen into the cytosol
@ast
A membrane protein complex med ...... the ER lumen into the cytosol
@en
A membrane protein complex med ...... the ER lumen into the cytosol
@en-gb
A membrane protein complex med ...... the ER lumen into the cytosol
@nl
prefLabel
A membrane protein complex med ...... the ER lumen into the cytosol
@ast
A membrane protein complex med ...... the ER lumen into the cytosol
@en
A membrane protein complex med ...... the ER lumen into the cytosol
@en-gb
A membrane protein complex med ...... the ER lumen into the cytosol
@nl
P2093
P2860
P921
P3181
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P1476
A membrane protein complex med ...... the ER lumen into the cytosol.
@en
P2093
P2860
P2888
P3181
P356
10.1038/NATURE02656
P407
P577
2004-06-24T00:00:00Z
P5875
P6179
1050431257