Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
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Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginineDifferential coupling of m2 and m4 muscarinic receptors to inhibition of adenylyl cyclase by Gi alpha and G(o)alpha subunitsMuscarinic acetylcholine receptor subtypes as agonist-dependent oncogenesIdentification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2Nerve growth factor regulation of m4 muscarinic receptor mRNA stability but not gene transcription requires mitogen-activated protein kinase activityMuscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activationRTA, a candidate G protein-coupled receptor: cloning, sequencing, and tissue distribution.Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorderNovel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunityDrug Development in Alzheimer's Disease: The Contribution of PET and SPECTBeneficial effects of estrogen in a mouse model of cerebrovascular insufficiencyTyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrixNeuromodulation of Na+ channels: an unexpected form of cellular plasticityDiscovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatinsMapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptorSelectivity profile of the novel muscarinic antagonist UH-AH 37 determined by the use of cloned receptors and isolated tissue preparationsPC12 phaeochromocytoma cells contain an atypical muscarinic receptor binding siteScopolamine administration modulates muscarinic, nicotinic and NMDA receptor systemsMuscarinic acetylcholine receptor regulation of TRP6 Ca2+ channel isoforms. Molecular structures and functional characterizationDifferent single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor familyMucosa-dependent muscarinic liberation of prostaglandins from rat isolated tracheaMuscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain.Chronic ethanol exposure enhances signaling through muscarinic receptors expressed by cRNA injection in Xenopus oocytes: implications for mechanism of action.Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders.Selective activation of M4 muscarinic acetylcholine receptors reverses MK-801-induced behavioral impairments and enhances associative learning in rodents.Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophreniaMuscarinic acetylcholine receptor subtype expression in avian vestibular hair cells, nerve terminals and ganglion cellsSynthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists.The mouse dopamine D2A receptor gene: sequence homology with the rat and human genes and expression of alternative transcripts.Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesSynthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen.Chemical lead optimization of a pan G(q) mAChR M(1), M(3), M(5) positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M(5) PAM.Synthesis and SAR of N-(4-(4-alklylpiperazin-1-yl)phenyl)benzamides as muscarinic acetylcholine receptor subtype 1 (M1) anatgonists.A conserved motif in the membrane proximal C-terminal tail of human muscarinic m1 acetylcholine receptors affects plasma membrane expression.Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cellsSomatodendritic targeting of M5 muscarinic receptor in the rat ventral tegmental area: implications for mesolimbic dopamine transmissionExpression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal gangliaThe muscarinic M(5) receptor: a silent or emerging subtype?Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice.
P2860
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P2860
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
description
1988 nî lūn-bûn
@nan
1988 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@ast
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en-gb
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@nl
type
label
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@ast
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en-gb
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@nl
prefLabel
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@ast
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en-gb
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@nl
P2093
P921
P3181
P1433
P1476
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
@en
P2093
N J Buckley
T I Bonner
P304
P3181
P356
10.1016/0896-6273(88)90190-0
P407
P577
1988-07-01T00:00:00Z