Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells
about
PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).Evolutionary emergence of a novel splice variant with an opposite effect on the cell cycle.Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis.TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation.Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancerPromoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.Small Molecule Inhibitors of Protein Arginine Methyltransferases.Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferationCellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors.Inhibitor of differentiation 4 (ID4): From development to cancerSelective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations.Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells.Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer.High nuclear expression of protein arginine methyltransferase-5 is a potentially useful marker to estimate submucosal invasion in endoscopically resected early colorectal carcinoma.Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth.Proliferative role of TRAF4 in breast cancer by upregulating PRMT5 nuclear expression.Targeting protein arginine methyltransferase 5 in disease.Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression.Protein arginine methylation: an emerging regulator of the cell cycle.Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients
P2860
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P2860
Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@ast
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en-gb
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@nl
type
label
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@ast
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en-gb
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@nl
prefLabel
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@ast
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en-gb
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@nl
P2093
P2860
P3181
P1433
P1476
Protein arginine methyltransfe ...... cleus of prostate cancer cells
@en
P2093
Chidan Wan
Zhengxin Wang
Zhongping Gu
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0044033
P407
P577
2012-01-01T00:00:00Z