Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase
about
RhoD binds the Rab5 effector Rabankyrin-5 and has a role in trafficking of the platelet-derived growth factor receptorPrenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingAvl9p, a member of a novel protein superfamily, functions in the late secretory pathway.The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathwayRhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac.RhoB deficiency in thymic medullary epithelium leads to early thymic atrophyRhoB regulates PDGFR-beta trafficking and signaling in vascular smooth muscle cells.Simultaneous irradiation of fibroblasts and carcinoma cells repress the secretion of soluble factors able to stimulate carcinoma cell migration.Aberrant signaling pathways in squamous cell lung carcinoma.Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth.GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.ROCK I-mediated activation of NF-kappaB by RhoBRhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production.Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells.Cdc42: an effector and regulator of ErbB1 as a strategic target in breast cancer therapy.Roles of rho GTPases in intracellular transport and cellular transformation.RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell borderThe mechanisms and significance of up-regulation of RhoB expression by hypoxia and glucocorticoid in rat lung and A549 cells.Chemical approaches to mapping the function of post-translational modifications.RhoB plays an essential role in CXCR2 sorting decisions.Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulationRhoB regulates the function of macrophages in the hypoxia-induced inflammatory response.The role of small GTPases in neuronal morphogenesis and polarity.RhoA, RhoB and RhoC have different roles in cancer cell migration.Rho GTPases modulate malignant transformation of tumor cells.ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation.The RhoB small GTPase in physiology and disease.Altered apoptotic responses in neurons lacking RhoB GTPase.MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling.Progesterone Inhibits Endothelial Cell Migration Through Suppression of the Rho Activity Mediated by cSrc Activation.Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxiaHrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesiclesRho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification.Immunohistological study of small Rho GTPases and β-catenin during regeneration of the rat submandibular gland.The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.RhoB: Team Oncogene or Team Tumor Suppressor?Characterizing the interactions of two lipid modifications with lipid rafts: farnesyl anchors vs. palmitoyl anchors.RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3.KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration
P2860
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P2860
Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@ast
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en-gb
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@nl
type
label
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@ast
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en-gb
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@nl
prefLabel
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@ast
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en-gb
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@nl
P50
P3181
P356
P1476
Farnesyltransferase inhibitors ...... modulation of the RhoB GTPase
@en
P2093
Matthew Wherlock
P304
P3181
P356
10.1242/JCS.01193
P407
P577
2004-07-01T00:00:00Z