Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
about
Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosisCharacterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosisPrion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cellsGlial cells as intrinsic components of non-cell-autonomous neurodegenerative diseaseTransmission and spreading of tauopathy in transgenic mouse brainXBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagyGolgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport VesiclesALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium TriadEndoplasmic Reticulum Stress Interacts With Inflammation in Human DiseasesPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersThe microglial-motoneuron dialogue in ALSProteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson diseaseMicroglia centered pathogenesis in ALS: insights in cell interconnectivityIn Vivo imaging reveals distinct inflammatory activity of CNS microglia versus PNS macrophages in a mouse model for ALSThe Cu, Zn Superoxide Dismutase: Not Only a Dismutase EnzymeThe complex molecular biology of amyotrophic lateral sclerosis (ALS)Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkersMonitoring CSF proteome alterations in amyotrophic lateral sclerosis: obstacles and perspectives in translating a novel marker panel to the clinicMechanisms underlying inflammation in neurodegenerationIntermolecular transmission of superoxide dismutase 1 misfolding in living cells.Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons.Cerebrospinal fluid concentrations of peptides derived from chromogranin B and secretogranin II are decreased in multiple sclerosis.Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila modelsChromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis.Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosisInflammation in ALS and SMA: sorting out the good from the evil.Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis.Modelling amyotrophic lateral sclerosis: progress and possibilitiesSOD1, an unexpected novel target for cancer therapyNeuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microgliaBiological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS.D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosisMutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis.Mitochondrial dysfunction and intracellular calcium dysregulation in ALSMisfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALSChromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytesCytotoxicity of superoxide dismutase 1 in cultured cells is linked to Zn2+ chelation.Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.Hyperphosphorylation and cleavage at D421 enhance tau secretion
P2860
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P2860
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@ast
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en-gb
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@nl
type
label
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@ast
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en-gb
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@nl
prefLabel
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@ast
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en-gb
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@nl
P2093
P921
P3181
P356
P1433
P1476
Chromogranin-mediated secretio ...... amyotrophic lateral sclerosis
@en
P2093
Attila Sik
Jean-Pierre Julien
Nobuyuki Nukina
Ryosuke Takahashi
Takashi Sakurai
P2888
P304
P3181
P356
10.1038/NN1603
P407
P577
2005-12-20T00:00:00Z
P6179
1051134476