A novel adaptation of the integrin PSI domain revealed from its crystal structure
about
Molecular dynamics simulations of forced unbending of integrin α(v)β₃Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantavirusesA structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrinsA novel structural fold in polysaccharide lyases: Bacillus subtilis family 11 rhamnogalacturonan lyase YesW with an eight-bladed beta-propellerStructure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied ForcesCrystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragmentα(V)β(3) integrin crystal structures and their functional implicationsIntegrin α1 Has a Long Helix, Extending from the Transmembrane Region to the Cytoplasmic Tail in Detergent MicellesPlatelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapiesStructural basis of integrin regulation and signalingIntegrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach.Multivalent presentation of antihantavirus peptides on nanoparticles enhances infection blockadeA naturally occurring LeuVal mutation in beta3-integrin impairs the HPA-1a epitope: the third allele of HPA-1.Rapid detection of HPA-1 alloantibodies by platelet antigens immobilized onto microbeads.Immunologic and structural analysis of eight novel domain-deletion beta3 integrin peptides designed for detection of HPA-1 antibodies.Phage display selection of cyclic peptides that inhibit Andes virus infection.Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606.Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3.The α-subunit regulates stability of the metal ion at the ligand-associated metal ion-binding site in β3 integrins.Conservation of the human integrin-type beta-propeller domain in bacteria.Structural diversity in integrin/talin interactions.The effect of the single substitution of arginine within the RGD tripeptide motif of a modified neurotoxin dendroaspin on its activity of platelet aggregation and cell adhesion.Metal ion and ligand binding of integrin α5β1Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function.Early chordate origin of the vertebrate integrin αI domains.β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons.The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation.Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin.Conserved fiber-penton base interaction revealed by nearly atomic resolution cryo-electron microscopy of the structure of adenovirus provides insight into receptor interaction.Integrin structures and conformational signalingStructure and mechanics of integrin-based cell adhesion.Small molecule inhibitors of hantavirus infectionMutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.The role of integrins in cancer and the development of anti-integrin therapeutic agents for cancer therapy.Integrin structure, activation, and interactionsPlexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Low affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection.Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.Cryo-electron microscopy structure of an adenovirus-integrin complex indicates conformational changes in both penton base and integrin.
P2860
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P2860
A novel adaptation of the integrin PSI domain revealed from its crystal structure
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@ast
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@en
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@nl
type
label
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@ast
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@en
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@nl
prefLabel
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@ast
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@en
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@nl
P2093
P2860
P3181
P356
P1476
A novel adaptation of the integrin PSI domain revealed from its crystal structure
@en
P2093
Jian-Ping Xiong
M Amin Arnaout
Simon L Goodman
P2860
P304
P3181
P356
10.1074/JBC.C400362200
P407
P50
P577
2004-09-24T00:00:00Z