Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
about
Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitisProtease inhibition as new therapeutic strategy for GI diseasesKLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton SyndromeDeimination of human filaggrin-2 promotes its proteolysis by calpain 1The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' familyUnlocking the potential of orphan legumes.Evolutionary history of tissue kallikreinsLowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown.Elastase and tryptase govern TNFα-mediated production of active chemerin by adipocytes.Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin graftsHuman involucrin promoter mediates repression-resistant and compartment-specific LEKTI expressionSynergy of understanding dermatologic disease and epidermal biology.Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skinKLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting.Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.The role of filaggrin in the atopic diathesis.Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases.Proteases and proteomics: cutting to the core of human skin pathologies.Epidermal barriersMolecular basis for stratum corneum maturation and moisturization.Inherited desmosomal disorders.Betapapillomavirus in multiple non-melanoma skin cancers of Netherton syndrome: Case report and published work review.Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis.Skin barrier function and its importance at the start of the atopic marchSerine protease inhibitors to treat inflammation: a patent review (2011-2016).Coffee polyphenols extracted from green coffee beans improve skin properties and microcirculatory function.Cytoplasmic proteases cleave Profilaggrin producing FilaggrinKLK5 cleaves and activates CELA2
P2860
Q24632061-3773F6C3-7D87-4ABD-BB97-75962AA5B06AQ26747722-70C1E96E-AC7F-41CC-BEE0-3ED5CF6DF314Q27310680-43BF3F4B-1149-44DB-9739-FC65A8491DF1Q28118423-19D35C27-D52A-468D-85D2-077CAAFAF417Q28264599-38B2C190-DE6A-4D97-977D-530588E9F3A1Q31150515-ED9D3D84-2C52-471D-AC12-7449FD562A35Q33745045-BB5280B5-D492-48D7-B3CD-E264E52C58D3Q33811938-C7B813F6-EB6F-46FE-989F-DBF2713A180FQ34507219-6E10405A-C2E0-4C3B-81FC-D2DE7849A1B9Q34556821-ECD19E13-3D4A-4A9E-B165-ECE4DE90E006Q35678420-17AAD30E-626E-4F11-ACDD-40BF72F03615Q35699059-5BD73591-DC1F-46BD-A2D3-769C412F5894Q36043453-871E45EB-9D35-4148-B31C-F7898BD0218CQ36251167-A9AFA1EE-ACB7-46E5-9A75-C1FE9AEBA362Q37218675-45DAD53A-45EA-4D05-970D-3050D5A70413Q37630234-33B57CD1-3B5D-4879-A5AC-040C1F37BC96Q37774023-FFC8D832-6299-4CA4-AA24-0F8B3A604DD5Q37980290-33E45334-410F-4CCE-A73D-7CAEDAD8D9C7Q38200069-34E5364D-830A-41C1-B365-57C63AA21B3AQ38201396-132D7023-6896-4382-A284-1085A9AE0DEDQ38252384-FE6321C5-E375-4F91-873F-C39F39C23A42Q38285372-343571C0-33A2-4D04-8709-FED3798A3046Q38445240-BFEE22C1-833E-4E3D-8E31-2A35F5523951Q38959847-C2AA951E-AF49-450C-B5FF-1A54BF369718Q39614319-B2C291AD-8BB9-4E58-820D-D2F4E8209599Q47368493-1460ABD9-2954-4C8E-A707-588D4CFD4C05Q47710438-D1D42C90-6FB1-4139-AE68-8FE8E04475ADQ50288518-9981F494-D4B0-414D-A498-93E293EA9F75Q50288537-291B7707-54C6-4438-B4B7-6B90A9FBE941
P2860
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@ast
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en-gb
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@nl
type
label
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@ast
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en-gb
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@nl
prefLabel
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@ast
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en-gb
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@nl
P2093
P2860
P921
P3181
P356
P1476
Elastase 2 is expressed in hum ...... aggrin and lipid misprocessing
@en
P2093
Aurélie Robin
Bernard Monsarrat
Chrystelle Bonnart
Céline Besson
Céline Deraison
Laurence Lamant
Marie Gonthier
Matthieu Lacroix
Pierre Dubus
Yoshikazu Uchida
P2860
P304
P3181
P356
10.1172/JCI41440
P407
P577
2010-03-01T00:00:00Z