TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals
about
Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipidsGenome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity.Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.Substrate-attached materials are enriched with tetraspanins and are analogous to the structures associated with rear-end retraction in migrating cells.Metalloproteolytic receptor shedding…platelets "acting their age".Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasis.Viruses and tetraspanins: lessons from single molecule approaches.Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro.Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies.Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling.Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegansPhysical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.ADAM Proteases and Gastrointestinal Function.Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci.TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomicsEvolutionary Dynamics of Abundant Stop Codon Readthrough.Tspan5 is an independent favourable prognostic factor and suppresses tumour growth in gastric cancerTetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.Tetraspanins Function as Regulators of Cellular Signaling.Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration.Tetraspanins in extracellular vesicle formation and function.TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS.Tspan33 is Expressed in Transitional and Memory B Cells, but is not Responsible for High ADAM10 Expression.New insights into the tetraspanin Tspan5 using novel monoclonal antibodies.The Emerging Role of Tetraspanins in the Proteolytic Processing of the Amyloid Precursor Protein.Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.A mutation in the human tetraspanin CD81 gene is expressed as a truncated protein but does not enable CD19 maturation and cell surface expression.The Role of ADAM10 in Alzheimer's Disease.Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins.Control of the Inflammatory Macrophage Transcriptional Signature by miR-155.ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration.Tools and methods for studying Notch signaling in Drosophila melanogaster.Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10.Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer's Disease Treatment.The Tetraspanin TSPAN33 Controls TLR-Triggered Macrophage Activation through Modulation of NOTCH Signaling.Genome-Wide Screen for New Components of the Drosophila melanogaster Torso Receptor Tyrosine Kinase Pathway.
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P248
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P2860
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@ast
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en-gb
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@nl
type
label
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@ast
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en-gb
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@nl
prefLabel
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@ast
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en-gb
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@nl
P2093
P2860
P50
P921
P3181
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P1476
TspanC8 tetraspanins regulate ...... ctivation in flies and mammals
@en
P2093
François Schweisguth
Jean-François Ottavi
Philippe Mauduit
P2860
P304
P3181
P356
10.1083/JCB.201201133
P407
P577
2012-10-29T00:00:00Z