Structure and functional analysis of the IGF-II/IGF2R interaction
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Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptorDominant-negative effect of truncated mannose 6-phosphate/insulin-like growth factor II receptor species in cancerCation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sitesAn exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptorStructure of the Lectin Mannose 6-Phosphate Receptor Homology (MRH) Domain of Glucosidase II, an Enzyme That Regulates Glycoprotein Folding Quality Control in the Endoplasmic ReticulumModification of a small β-barrel protein, to give pseudo-amyloid structures, inhibits amyloid β-peptide aggregation.On computational approaches for size-and-shape distributions from sedimentation velocity analytical ultracentrifugation.Targeting non-small cell lung cancer cells by dual inhibition of the insulin receptor and the insulin-like growth factor-1 receptorIdentification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor.Glucosidase II and MRH-domain containing proteins in the secretory pathway.Rapid molecular evolution across amniotes of the IIS/TOR network.The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-RatElucidating the Activation Mechanism of the Insulin-Family Proteins with Molecular Dynamics Simulations.Differential gene expression in granulosa cells from polycystic ovary syndrome patients with and without insulin resistance: identification of susceptibility gene sets through network analysisFunctional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonistStructure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growthStrategies for carbohydrate recognition by the mannose 6-phosphate receptors.High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor.Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansionCarbohydrate recognition by the mannose-6-phosphate receptorsASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.Type I insulin-like growth factor receptor signaling in hematological malignancies.The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non-small cell lung cancer.Mannose 6-phosphate receptor homology (MRH) domain-containing lectins in the secretory pathway.Ganitumab for the treatment of small-cell lung cancer.Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells.Biochemical characterization of individual human glycosylated pro-insulin-like growth factor (IGF)-II and big-IGF-II isoforms associated with cancer.An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.Renin and the IGFII/M6P receptor system in cardiac biology.How ligand binds to the type 1 insulin-like growth factor receptor.Detection of Selection Signatures in Chinese Landrace and Yorkshire Pigs Based on Genotyping-by-Sequencing Data.Macromolecular Complexes
P2860
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P2860
Structure and functional analysis of the IGF-II/IGF2R interaction
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure and functional analysis of the IGF-II/IGF2R interaction
@ast
Structure and functional analysis of the IGF-II/IGF2R interaction
@en
Structure and functional analysis of the IGF-II/IGF2R interaction
@en-gb
Structure and functional analysis of the IGF-II/IGF2R interaction
@nl
type
label
Structure and functional analysis of the IGF-II/IGF2R interaction
@ast
Structure and functional analysis of the IGF-II/IGF2R interaction
@en
Structure and functional analysis of the IGF-II/IGF2R interaction
@en-gb
Structure and functional analysis of the IGF-II/IGF2R interaction
@nl
prefLabel
Structure and functional analysis of the IGF-II/IGF2R interaction
@ast
Structure and functional analysis of the IGF-II/IGF2R interaction
@en
Structure and functional analysis of the IGF-II/IGF2R interaction
@en-gb
Structure and functional analysis of the IGF-II/IGF2R interaction
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structure and functional analysis of the IGF-II/IGF2R interaction
@en
P2093
Adam Denley
Carlie Delaine
Christian Siebold
Gijs van Boxel
James Brown
John C Wallace
Oliver J Zaccheo
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601938
P407
P577
2007-11-29T00:00:00Z