Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope
about
The role of lipoxygenases in pathophysiology; new insights and future perspectivesEicosanoids and Keratinocytes in Wound HealingMammalian lipoxygenases and their biological relevanceDiscovery of essential fatty acidsBiosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acidThe importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrierThe structural basis for specificity in lipoxygenase catalysis.Ultrastructure of skin from Refsum disease with emphasis on epidermal lamellar bodies and stratum corneum barrier lipid organization.Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation.Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions.Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development8R-Lipoxygenase-catalyzed synthesis of a prominent cis-epoxyalcohol from dihomo-γ-linolenic acid: a distinctive transformation compared with S-lipoxygenases.Quantitative determination of 12-hydroxyeicosatetraenoic acids by chiral liquid chromatography tandem mass spectrometry in a murine atopic dermatitis model.Essential fatty acids: the work of George and Mildred Burr.Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function.Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.The effect of varying ratios of docosahexaenoic acid and arachidonic acid in the prevention and reversal of biochemical essential fatty acid deficiency in a murine model.The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE.Pathogenesis-based therapies in ichthyoses.Formation and functions of the corneocyte lipid envelope (CLE).Epidermal barriersMolecular basis for stratum corneum maturation and moisturization.Lipid oxidation in the skin.Arachidonic acid needed in infant formula when docosahexaenoic acid is present.Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers.12/15-Lipoxygenase deficiency reduces densities of mesenchymal stem cells in the dermis of wounded and unwounded skinCrystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein.A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch.Structural identification of skin ceramides containing ω-hydroxy acyl chains using mass spectrometry.The biotin-ligating protein BPL-1 is critical for lipid biosynthesis and polarization of the Caenorhabditis elegans embryo.Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.Naturally occurring ω-Hydroxyacids.Inherited Nonsyndromic Ichthyoses: An Update on Pathophysiology, Diagnosis and Treatment.Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function.Fatty acids and related lipid mediators in the regulation of cutaneous inflammation.ALOXE3 isomerises 12R-HpETE to HXA3Diminished protein-bound ω-hydroxylated ceramides in the skin of patients with ichthyosis with 12R-lipoxygenase (LOX) or eLOX-3 deficiency.A synthetic C16 omega-hydroxyphytoceramide improves skin barrier functions from diversely perturbed epidermal conditions.Morphological alterations in two siblings with autosomal recessive congenital ichthyosis associated with CYP4F22 mutations.
P2860
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P2860
Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@ast
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en-gb
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@nl
type
label
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@ast
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en-gb
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@nl
prefLabel
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@ast
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en-gb
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@nl
P2093
P2860
P921
P3181
P356
P1476
Lipoxygenases mediate the effe ...... the corneocyte lipid envelope
@en
P2093
Alan R Brash
David R Beier
Debra Crumrine
Huiyong Yin
Peter M Elias
William E Boeglin
Yuxiang Zheng
P2860
P304
P3181
P356
10.1074/JBC.M111.251496
P407
P577
2011-07-08T00:00:00Z