A novel role for XIAP in copper homeostasis through regulation of MURR1
about
Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cellsRegulation of the copper chaperone CCS by XIAP-mediated ubiquitinationXIAP: cell death regulation meets copper homeostasisCOMMD1 downregulates the epithelial sodium channel through Nedd4-2XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signalingCOMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7ACharacterization of COMMD protein-protein interactions in NF-kappaB signallingCOMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) bindingTumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphateCOMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligaseCCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signalingMolecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypesSolution structure of the COMMD1 N-terminal domainDifferential expression of copper-associated and oxidative stress related proteins in a new variant of copper toxicosis in Doberman pinschersCharting the travels of copper in eukaryotes from yeast to mammalsCrystal Structure of the BIR1 Domain of XIAP in Two Crystal FormsX-linked lymphoproliferative syndromes: brothers or distant cousins?The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expressionX-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motilityLiver-specific Commd1 knockout mice are susceptible to hepatic copper accumulationUnique anti-apoptotic activity of EAAC1 in injured motor neuronsIncreased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null miceRegulation of NF-κB activity by competition between RelA acetylation and ubiquitinationNH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cellsGCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelACOMMD1-deficient dogs accumulate copper in hepatocytes and provide a good model for chronic hepatitis and fibrosisThe puzzle posed by COMMD1, a newly discovered protein binding Cu(II)."Pulling the plug" on cellular copper: the role of mitochondria in copper export.Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivoCharting the landscape of tandem BRCT domain-mediated protein interactions.Copper toxicosis gene MURR1 is not changed in Wilson disease patients with normal blood ceruloplasmin levels.COMMD1-mediated ubiquitination regulates CFTR trafficking.E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activityX-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton.Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7BCanine models of copper toxicosis for understanding mammalian copper metabolism.Hepatic Copper Accumulation: A Novel Feature in Transient Infantile Liver Failure Due to TRMU Mutations?Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradationInhibitor of apoptosis proteins as intracellular signaling intermediates.
P2860
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P2860
A novel role for XIAP in copper homeostasis through regulation of MURR1
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2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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name
A novel role for XIAP in copper homeostasis through regulation of MURR1
@ast
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en-gb
A novel role for XIAP in copper homeostasis through regulation of MURR1
@nl
type
label
A novel role for XIAP in copper homeostasis through regulation of MURR1
@ast
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en-gb
A novel role for XIAP in copper homeostasis through regulation of MURR1
@nl
prefLabel
A novel role for XIAP in copper homeostasis through regulation of MURR1
@ast
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en-gb
A novel role for XIAP in copper homeostasis through regulation of MURR1
@nl
P2093
P2860
P50
P356
P1433
P1476
A novel role for XIAP in copper homeostasis through regulation of MURR1
@en
P2093
Bart van De Sluis
Colin S Duckett
George J Brewer
John C Wilkinson
Lakshmanan Ganesh
Leo W J Klomp
Robert D Dick
P2860
P304
P356
10.1038/SJ.EMBOJ.7600031
P407
P577
2003-12-18T00:00:00Z