Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization from down-regulation of calcium channel activity
about
Structure-function studies of the G-domain from human gem, a novel small G-proteinMolecular mechanisms of activity-dependent changes in dendritic morphology: role of RGK proteinsActivity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase IIαThe ß subunit of voltage-gated Ca2+ channelsAncient origins of RGK protein function: modulation of voltage-gated calcium channels preceded the protostome and deuterostome split.Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handlingPlasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition.Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission.The role of Rho GTPase proteins in CNS neuronal migration.Molecular determinants of Gem protein inhibition of P/Q-type Ca2+ channelsDose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPasesThe RGK family of GTP-binding proteins: regulators of voltage-dependent calcium channels and cytoskeleton remodeling.Rem inhibits skeletal muscle EC coupling by reducing the number of functional L-type Ca2+ channels.Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids.CaMKII-dependent phosphorylation of the GTPase Rem2 is required to restrict dendritic complexity.Ion channel regulation by Ras, Rho, and Rab small GTPases.Regulation of voltage-dependent calcium channels by RGK proteins.RGK regulation of voltage-gated calcium channels.Functional assessment of three Rem residues identified as critical for interactions with Ca(2+) channel β subunits.Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase.Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.Roles of 14-3-3 and calmodulin binding in subcellular localization and function of the small G-protein Rem2.RhoE function is regulated by ROCK I-mediated phosphorylation.Rad and Rem are non-canonical G-proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation.Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway.Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling.Molecular mechanisms and physiological relevance of RGK proteins in the heart.Gem GTPase and tau: morphological changes induced by gem GTPase in cho cells are antagonized by tau.Increased expression of Gem after rat sciatic nerve injury.
P2860
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P2860
Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization from down-regulation of calcium channel activity
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Phosphorylation of critical se ...... on of calcium channel activity
@ast
Phosphorylation of critical se ...... on of calcium channel activity
@en
Phosphorylation of critical se ...... on of calcium channel activity
@en-gb
Phosphorylation of critical se ...... on of calcium channel activity
@nl
type
label
Phosphorylation of critical se ...... on of calcium channel activity
@ast
Phosphorylation of critical se ...... on of calcium channel activity
@en
Phosphorylation of critical se ...... on of calcium channel activity
@en-gb
Phosphorylation of critical se ...... on of calcium channel activity
@nl
prefLabel
Phosphorylation of critical se ...... on of calcium channel activity
@ast
Phosphorylation of critical se ...... on of calcium channel activity
@en
Phosphorylation of critical se ...... on of calcium channel activity
@en-gb
Phosphorylation of critical se ...... on of calcium channel activity
@nl
P2093
P2860
P921
P1476
Phosphorylation of critical se ...... on of calcium channel activity
@en
P2093
P2860
P304
P356
10.1128/MCB.24.2.651-661.2004
P407
P577
2004-01-01T00:00:00Z