A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes
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A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal componentsRelative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasomehRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complexAssociation of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1An emerging model for BAP1's role in regulating cell cycle progressionRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathFunctions of the 19S complex in proteasomal degradationProteasome subunit Rpn13 is a novel ubiquitin receptorUbiquitin docking at the proteasome through a novel pleckstrin-homology domain interactionStructure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chainsStructural characterization of human Uch37Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzymeStabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo SpecificityMechanism of the Rpn13-induced activation of Uch37Structure characterization of the 26S proteasome.Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome.Autoregulation of the 26S proteasome by in situ ubiquitinationLocalization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopyComplete subunit architecture of the proteasome regulatory particleMolecular architecture of the 26S proteasome holocomplex determined by an integrative approachRpn1 and Rpn2 coordinate ubiquitin processing factors at proteasomeConformational switching of the 26S proteasome enables substrate degradationCharacterisation of the Trichinella spiralis deubiquitinating enzyme, TsUCH37, an evolutionarily conserved proteasome interaction partnerRegulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse developmentPAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasisRecognition and processing of ubiquitin-protein conjugates by the proteasomeEnhancement of proteasome activity by a small-molecule inhibitor of USP14Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).Purification, crystallization and preliminary X-ray data collection of the N-terminal domain of the 26S proteasome regulatory subunit p27 and its complex with the ATPase domain of Rpt5 from Mus musculusA global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarityViable mouse gene ablations that robustly alter brain Aβ levels are rare.Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targetsInherent asymmetry in the 26S proteasome is defined by the ubiquitin receptor RPN13Slipping up: partial substrate degradation by ATP-dependent proteases.Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradationMTMDAT-HADDOCK: high-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry
P2860
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P248
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P2860
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@ast
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en-gb
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@nl
type
label
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@ast
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en-gb
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@nl
prefLabel
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@ast
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en-gb
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
A novel proteasome interacting ...... nzyme UCH37 to 26S proteasomes
@en
P2093
Hideki Yashiroda
Jun Hamazaki
Keiji Tanaka
Shun-Ichiro Iemura
Tohru Natsume
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601338
P407
P577
2006-09-21T00:00:00Z