A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95
about
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activityThe Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1Therapeutic use of PDZ protein-protein interaction antagonismInhibition of N-Methyl-D-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane PotentialQuantifying the effects of elastic collisions and non-covalent binding on glutamate receptor trafficking in the post-synaptic densityPost-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95Targeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein familyBeyond the binding site: the role of the β₂-β₃ loop and extra-domain structures in PDZ domainsA chemical library approach to organic-modified peptide ligands for PDZ domain proteins: a synthetic, thermodynamic and structural investigation.Binding free energy landscape of domain-peptide interactions.Structural and thermodynamic analysis of PDZ-ligand interactions.Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domainThe interconversion between a flexible β-sheet and a fibril β-arrangement constitutes the main conformational event during misfolding of PSD95-PDZ3 domainExploring Protein-Peptide Binding Specificity through Computational Peptide ScreeningProtein purification using PDZ affinity chromatography.Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer.Ligand binding to the PDZ domains of postsynaptic density protein 95.Bivalent peptides as PDZ domain ligands.Ligand binding site identification by higher dimension molecular dynamicsTargeting GIPC/synectin in pancreatic cancer inhibits tumor growth.Ligand binding by PDZ domains.Posttranslational Modifications Regulate the Postsynaptic Localization of PSD-95.Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth.A cyclic peptide targeted against PSD-95 blocks central sensitization and attenuates thermal hyperalgesia.Learning sequence determinants of protein:protein interaction specificity with sparse graphical models.Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions.The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling.Simultaneous prediction of binding free energy and specificity for PDZ domain-peptide interactions.A physical model for PDZ-domain/peptide interactions.Molecular mechanism investigation of the neutralization of cadmium toxicity by transferrin.
P2860
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P2860
A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@ast
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en-gb
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@nl
type
label
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@ast
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en-gb
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@nl
prefLabel
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@ast
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en-gb
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@nl
P2093
P2860
P921
P356
P1433
P1476
A thermodynamic ligand binding ...... malian neuronal protein PSD-95
@en
P2093
Azrael Paredes
Chamila Rupasinghe
Dorina Saro
Mark R Spaller
Nicole Caspers
P2860
P304
P356
10.1021/BI062088K
P407
P577
2007-05-29T00:00:00Z