Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
about
The transcription factor p53: not a repressor, solely an activatorSerine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cellsA nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevityLinks between metabolism and cancerMicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancersTargeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer TherapyNeuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisIndependent origins of neurons and synapses: insights from ctenophoresCancer metabolism: key players in metabolic reprogrammingSerine and glycine metabolism in cancerRole of the p53 tumor suppressor in metabolismRedox control of glutamine utilization in cancerTumor suppressor p53 and its mutants in cancer metabolismP53/microRNA-34-induced metabolic regulation: new opportunities in anticancer therapyGlutamine and cancer: cell biology, physiology, and clinical opportunitiesCell cycle regulators guide mitochondrial activity in radiation-induced adaptive responseThe role of tumor suppressor p53 in the antioxidant defense and metabolismSexual Preferences in Nutrient Utilization Regulate Oxygen Consumption and Reactive Oxygen Species Generation in Schistosoma mansoni: Potential Implications for Parasite Redox BiologyMitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolismStructural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolismStructural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinomaPulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanismsSilencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cellsCytoprotection "gone astray": Nrf2 and its role in cancerChemical metabolic inhibitors for the treatment of blood-borne cancersRole of mitochondrial dysfunction in cancer progressionDNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescenceThe control of the metabolic switch in cancers by oncogenes and tumor suppressor genesMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway.More targets, more pathways and more clues for mutant p53.Mammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Ferroptosis: A missing puzzle piece in the p53 blueprint?p63 transcriptionally regulates the expression of matrix metallopeptidase 13.One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Altered metabolism in cancer.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response
P2860
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P2860
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@ast
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en-gb
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@nl
type
label
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@ast
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en-gb
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@nl
prefLabel
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@ast
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en-gb
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@nl
P2093
P2860
P50
P3181
P356
P1476
Phosphate-activated glutaminas ...... sm and reactive oxygen species
@en
P2093
Carol Prives
Eiichi Sato
Hidekazu Nagano
Ichiro Tatsuno
Koutaro Yokote
Maria Lokshin
Masha V Poyurovsky
Sawako Suzuki
Shuichi Ohkubo
Takafumi Mayama
P2860
P304
P3181
P356
10.1073/PNAS.1002459107
P407
P577
2010-04-20T00:00:00Z